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The influence of electronic screens on the health of children and adolescents and their education is not well understood. In this prospectively registered umbrella review (PROSPERO identifier CRD42017076051 ), we harmonized effects from 102 meta-analyses (2,451 primary studies; 1,937,501 participants) of screen time and outcomes. In total, 43 effects from 32 meta-analyses met our criteria for statistical certainty. Meta-analyses of associations between screen use and outcomes showed small-to-moderate effects (range: r = -0.14 to 0.33). In education, results were mixed; for example, screen use was negatively associated with literacy (r = -0.14, 95% confidence interval (CI) = -0.20 to -0.09, P ≤ 0.001, k = 38, N = 18,318), but this effect was positive when parents watched with their children (r = 0.15, 95% CI = 0.02 to 0.28, P = 0.028, k = 12, N = 6,083). In health, we found evidence for several small negative associations; for example, social media was associated with depression (r = 0.12, 95% CI = 0.05 to 0.19, P ≤ 0.001, k = 12, N = 93,740). Limitations of our review include the limited number of studies for each outcome, medium-to-high risk of bias in 95 out of 102 included meta-analyses and high heterogeneity (17 out of 22 in education and 20 out of 21 in health with I > 50%). We recommend that caregivers and policymakers carefully weigh the evidence for potential harms and benefits of specific types of screen use.
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http://dx.doi.org/10.1038/s41562-023-01712-8 | DOI Listing |
Clin Exp Dent Res
October 2025
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Objectives: This umbrella meta-analysis aimed to answer the clinical question: Do mini-screws and micro-implants improve specific orthodontic outcomes such as intermolar width, interpremolar width, suture expansion, molar movement, and skeletal width compared to conventional anchorage methods?
Materials And Methods: A systematic search was performed in PubMed, Scopus, ISI Web of Science, and Google Scholar up to October 2024. Systematic reviews and meta-analyses on mini-screws and micro-implants in orthodontic treatment were included. Methodological quality was assessed using AMSTAR 2, and a random-effects model was used to calculate effect sizes (ESs) and 95% confidence intervals (CIs).
Rep Pract Oncol Radiother
August 2025
Department of Oncology and Radiotherapy, University Hospital in Pilsen, Pilsen, Czech Republic.
In the recent years, the clinical stage where the cancer has spread beyond the primary site, but has not yet metastasised extensively, and which is known as oligometastatic disease (OMD), has become an object of interest to radiation oncologists. OMD is a kind of an "umbrella term" for a variety of clinical situations. This review focuses on the role of radiotherapy (RT) in the treatment of oligometastatic non-small cell lung cancer (OM-NSCLC).
View Article and Find Full Text PDFIntegr Pharm Res Pract
September 2025
Faculty of Health Sciences, Universidad Loyola Andalucia, Seville, Spain.
Background: Pharmaceutical care is currently being implemented in Polish community pharmacies, but remains unsupported by state funding, limiting its widespread adoption. In Spain pharmacists there provide a wide range of pharmaceutical care services.
Objective: The aim of the work is to understand how other countries, such as Spain, have approached pharmaceutical care, which may offer potential strategies.
Alzheimers Dement
September 2025
Multiomics Investigation of Neurodegenerative Diseases (MIND) Lab, Montréal, Québec, Canada.
Living with dementia requires decision making about numerous topics including daily activities and advance care planning (ACP). Both individuals living with dementia and care partners require informed support for decision making. We conducted an umbrella review to assess knowledge translation (KT) interventions supporting decision making for individuals living with dementia and their informal care partners.
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