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Cardiovascular diseases are responsible for almost 10,000 deaths annually in Aotearoa New Zealand. Almost a quarter of these are avoidable, increasing to half of all cardiovascular deaths for Māori and Pacific people. Health system reforms are an opportunity to set clear ambitious goals for improved heart health. This has been done for smoking, a cancer plan, mental health and diabetes among other health conditions. Given the scale of avoidable heart disease and avoidable heart health inequity, much of it due to people simply not accessing existing treatment options, there is no excuse not to deliver a national heart health action plan and we urge health policy makers to put it on the agenda.
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http://dx.doi.org/10.26635/6965.6283 | DOI Listing |
ESC Heart Fail
September 2025
Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.
Heart failure (HF) is a multifactorial and pathophysiological complex syndrome, involving not only neurohormonal activation but also oxidative stress, chronic low-grade inflammation, and metabolic derangements. Central to the cellular defence against oxidative damage is nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that orchestrates antioxidant and cytoprotective responses. Preclinical in vitro and in vivo studies reveal that Nrf2 signalling is consistently impaired in HF, contributing to the progression of myocardial dysfunction.
View Article and Find Full Text PDFCirc Cardiovasc Qual Outcomes
September 2025
Cardiology Department, Cardiac Intensive Care Unit, Hospital Vall Hebron, VHIR SIM CES Research Group, Universitat Autónoma de Barcelona, Spain (J.B.-R.).
Background: Effective risk communication is essential in managing cardiovascular disease, the leading cause of global mortality. Clear communication between patients and physicians supports informed decision-making, yet comprehension gaps persist. We aimed to assess the quality of risk communication during hospital admissions for cardiovascular events, from patient and physician perspectives, and identify discrepancies in risk perception and associated factors.
View Article and Find Full Text PDFThis article explores the potential of narrative medicine to strengthen the democratic ethos in health care. The heart of narrative medicine is attentive listening, an often scarce resource in our democratic communities. By listening to those who are traditionally voiceless and disenfranchised-the sick, the disabled, the old, the frail-narrative medicine empowers vulnerable patients' voices against the dominant discourse of health professionals and contributes to treating the moral injuries inflicted on patients by epistemic and social injustice.
View Article and Find Full Text PDFEur J Prev Cardiol
September 2025
Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Background And Aims: Data on cardiovascular outcomes and aortic growth in pregnant women with Turner syndrome is limited. We examine the cardiovascular and pregnancy outcomes in these women and analyze aortic growth throughout pregnancy.
Methods: The ROPAC III is a global, prospective, observational registry that enrolled pregnancies of women pre-pregnancy known with Turner syndrome from 2018 to 2023.
Eur J Prev Cardiol
September 2025
Department of Sport, Exercise and Health, Sports and Exercise Medicine, Medical Faculty, University of Basel, Basel, Switzerland.
The current guidelines for cardiovascular disease prevention by the European Society of Cardiology highlight the undisputable benefits of exercise and a physically active lifestyle for cardiovascular risk reduction. In addition to the health benefits of physical activity, observational data suggests that regular physical activity lowers all-cause mortality. However, this was not confirmed by Mendelian randomization studies and randomized controlled trials.
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