98%
921
2 minutes
20
Brain tumors pose a complex and urgent challenge in medical diagnostics, requiring precise and timely classification due to their diverse characteristics and potentially life-threatening consequences. While existing deep learning (DL)-based brain tumor classification (BTC) models have shown significant progress, they encounter limitations like restricted depth, vanishing gradient issues, and difficulties in capturing intricate features. To address these challenges, this paper proposes an efficient skip connections-based residual network (ESRNet). leveraging the residual network (ResNet) with skip connections. ESRNet ensures smooth gradient flow during training, mitigating the vanishing gradient problem. Additionally, the ESRNet architecture includes multiple stages with increasing numbers of residual blocks for improved feature learning and pattern recognition. ESRNet utilizes residual blocks from the ResNet architecture, featuring skip connections that enable identity mapping. Through direct addition of the input tensor to the convolutional layer output within each block, skip connections preserve the gradient flow. This mechanism prevents vanishing gradients, ensuring effective information propagation across network layers during training. Furthermore, ESRNet integrates efficient downsampling techniques and stabilizing batch normalization layers, which collectively contribute to its robust and reliable performance. Extensive experimental results reveal that ESRNet significantly outperforms other approaches in terms of accuracy, sensitivity, specificity, F-score, and Kappa statistics, with median values of 99.62%, 99.68%, 99.89%, 99.47%, and 99.42%, respectively. Moreover, the achieved minimum performance metrics, including accuracy (99.34%), sensitivity (99.47%), specificity (99.79%), F-score (99.04%), and Kappa statistics (99.21%), underscore the exceptional effectiveness of ESRNet for BTC. Therefore, the proposed ESRNet showcases exceptional performance and efficiency in BTC, holding the potential to revolutionize clinical diagnosis and treatment planning.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606037 | PMC |
http://dx.doi.org/10.3390/diagnostics13203234 | DOI Listing |
Clin J Am Soc Nephrol
September 2025
University College London Great Ormond Street Hospital for Children and Institute of Child Health, London, UK.
Background: Experience with icodextrin use in children on long-term peritoneal dialysis is limited. We describe international icodextrin prescription practices and their impact on clinical outcomes: ultrafiltration, blood pressure control, residual kidney function (RKF), technique and patient survival.
Methods: We included patients under 21 years enrolled in the International Pediatric Peritoneal Dialysis Network (IPPN) between 2007 and 2024, on automated PD with a daytime dwell.
Eur J Haematol
September 2025
Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.
Background: Clonotyping of immunoglobulin heavy chain (IGH) gene rearrangements is critical for diagnosis, prognostication, and measurable residual disease monitoring in chronic lymphocytic leukemia (CLL). Although short-read next-generation sequencing (NGS) platforms, such as Illumina MiSeq, are widely used, they face challenges in spanning full VDJ rearrangements. Long-read sequencing via Oxford Nanopore Technologies (ONT) offers a potential alternative using the compact and cost-effective flow cells.
View Article and Find Full Text PDFMagn Reson Med
September 2025
Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France.
Purpose: Fat fraction (FF) quantification in individual muscles using quantitative MRI is of major importance for monitoring disease progression and assessing disease severity in neuromuscular diseases. Undersampling of MRI acquisitions is commonly used to reduce scanning time. The present paper introduces novel unrolled neural networks for the reconstruction of undersampled MRI acquisitions.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
September 2025
Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
To investigate the clinicopathological features, diagnosis and differential diagnosis of primary bladder lymphoma. A retrospective study was conducted on 23 cases of primary bladder lymphoma diagnosed at Beijing Friendship Hospital of Capital Medical University between February 2010 and April 2024. The clinicopathological data were collected and analyzed, and literature was reviewed.
View Article and Find Full Text PDFInt J Audiol
September 2025
Centre for Digital Telecommunication Technologies, St. Petersburg Electrotechnical University "LETI", St. Petersburg, Russia.
Objective: To evaluate speech perception deficit compensation and predict potential hearing aids (HA) effectiveness in patients with hearing loss (HL).
Design: The patients underwent pure-tone audiometry and various speech tests in quiet (evaluating the peripheral auditory system and cognitive compensation) and in noise (to quantify central compensation through auditory processing and cognitive abilities).
Study Sample: 513 HL patients aged 19-93 years, including 403 HA users.