Green synthesis of N,S-doped carbon dots for tartrazine detection and their antibacterial activities.

A simple, green and low-cost method was developed for the synthesis of highly fluorescent N,S-doped carbon dots (N,S-CDs) the hydrothermal treatment of Gandha Prasarini (GP) leaves as a natural source of carbon, nitrogen and sulfur. The as-prepared N,S-CDs exhibited excitation-dependent green fluorescence emission ( = 450 nm, = 525 nm) with excellent stability, and were used as a fluorescent probe for the selective detection of tartrazine with a limit of detection of 0.18 μM. The fluorescence quenching of N,S-CDs was due to the inner filter effect. The developed method has been employed for the determination of tartrazine in honey and soft drinks with satisfactory recovery ranging from 92 to 110.2%. In addition, the antibacterial activity of the N,S-CDs was explored against both Gram-negative bacteria, () and (), and Gram-positive bacteria, (). The antibacterial mechanism of the N,S-CDs was investigated. The results indicated that the antibacterial activity was due to the membrane damage of the bacteria by the N,S-CDs. Besides, the N,S-CDs showed negligible lytic effects on human erythrocytes. These findings will inspire further exploitation of CD-based nano-bactericides in biomedical applications.