Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575304PMC
http://dx.doi.org/10.1093/af/vfad050DOI Listing

Publication Analysis

Top Keywords

development genetically
4
genetically improved
4
improved tropical-adapted
4
tropical-adapted dairy
4
dairy cattle
4
development
1
improved
1
tropical-adapted
1
dairy
1
cattle
1

Similar Publications

[Harnessing retroviral engineering for genome reprogramming].

Med Sci (Paris)

September 2025

CIRI, Centre international de recherche en infectiologie Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.

The accumulated knowledge on the biology of the HIV-1 virus has led to the emergence of technologies that exploit the architecture of retroviruses and their integration or vectorization properties. This field of study constitutes retroviral vectorology, democratized in laboratories by the use of lentiviral vectors. By hijacking retroviral assembly, other systems are emerging and are increasingly mentioned in recent literature.

View Article and Find Full Text PDF

Muricholic acid mediates puberty initiation via the hypothalamic TGR5 signaling pathway.

Proc Natl Acad Sci U S A

September 2025

Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China.

The onset of puberty is increasingly observed at earlier ages in children, especially in girls with obesity, a trend that predisposes them to long-term metabolic and reproductive disorders in adulthood. Bile acids have emerged as pivotal signaling molecules in both metabolic and reproductive disorders, but remain unexplored in the early onset of puberty in children. Herein, we find elevated levels of muricholic acid (MCA) species in the serum of girls with central precocious puberty, which strongly correlate with indices of hypothalamic-pituitary-gonadal axis activation and can reach peak levels during puberty among healthy children.

View Article and Find Full Text PDF

Dynamic and precise electromagnetic levitation of single cells.

Proc Natl Acad Sci U S A

September 2025

Molecular Imaging Program at Stanford, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304.

The biophysical properties of single cells are crucial for understanding cellular function and behavior in biology and medicine. However, precise manipulation of cells in 3-D microfluidic environments remains challenging, particularly for heterogeneous populations. Here, we present "Electro-LEV," a unique platform integrating electromagnetic and magnetic levitation principles for dynamic 3-D control of cell position during separation.

View Article and Find Full Text PDF

Microglia regulate neuronal circuit plasticity. Disrupting their homeostatic function has detrimental effects on neuronal circuit health. Neuroinflammation contributes to the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), with several microglial activation genes linked to increased risk for these conditions.

View Article and Find Full Text PDF

Ovulation is an intricate process that is essential for reproductive success. In , ovulation increases after mating. This increase is initiated by the male seminal fluid protein ovulin and is executed by female pathways, including octopamine (OA) neuronal signaling.

View Article and Find Full Text PDF