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Label noise hampers supervised training of neural networks. However, data without label noise is often infeasible to attain, especially for medical tasks. Attaining high-quality medical labels would require a pool of experts and their consensus reading, which would be extremely costly. Several methods have been proposed to mitigate the adverse effects of label noise during training. State-of-the-art methods use multiple networks that exploit different decision boundaries to identify label noise. Among the best performing methods is co-teaching. However, co-teaching comes with the requirement of knowing label noise a priori. Hence, we propose a co-teaching method that does not require any prior knowledge about the level of label noise. We introduce stochasticity to select or reject training instances. We have extensively evaluated the method on synthetic experiments with extreme label noise levels and applied it to real-world medical problems of ECG classification and cardiac MRI segmentation. Results show that the approach is robust to its hyperparameter choice and applies to various classification tasks with unknown levels of label noise.
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http://dx.doi.org/10.1038/s41598-023-43864-7 | DOI Listing |
J Chem Phys
September 2025
Department of Mathematics and Computer Science, Freie Universität, Berlin, Germany.
Coarse-grained (CG) molecular dynamics simulations extend the length and time scales of atomistic simulations by replacing groups of correlated atoms with CG beads. Machine-learned coarse-graining (MLCG) has recently emerged as a promising approach to construct highly accurate force fields for CG molecular dynamics. However, the calibration of MLCG force fields typically hinges on force matching, which demands extensive reference atomistic trajectories with corresponding force labels.
View Article and Find Full Text PDFAnal Chem
September 2025
State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong SAR 999077, China.
Mass spectrometry imaging (MSI) is a label-free technique that enables the visualization of the spatial distribution of thousands of ions within biosamples. Data denoising is the computational strategy aimed at enhancing the MSI data quality, providing an effective alternative to experimental methods. However, due to the complex noise pattern inherent in MSI data and the difficulty in obtaining ground truth from noise-free data, achieving reliable denoised images remains challenging.
View Article and Find Full Text PDFFront Digit Health
August 2025
Architecture Laboratory, Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan.
Background: Microwave Doppler sensors, capable of detecting minute physiological movements, enable the measurement of biometric information, such as walking patterns, heart rate, and respiration. Unlike fingerprint and facial recognition systems, they offer authentication without physical contact or privacy concerns. This study focuses on non-contact seismocardiography using microwave Doppler sensors and aims to apply this technology for biometric authentication.
View Article and Find Full Text PDFJ Acoust Soc Am
September 2025
Centre de Vision Numérique, CentraleSupélec, Université Paris-Saclay, Inria, Gif-Sur-Yvette, France.
Conventional techniques for underwater source localization have traditionally relied on optimization methods, matched-field processing, beamforming, and, more recently, deep learning. However, these methods often fall short to fully exploit the data correlation crucial for accurate source localization. This correlation can be effectively captured using graphs, which consider the spatial relationship among data points through edges.
View Article and Find Full Text PDFBiol Reprod
September 2025
Département des sciences animales, Faculté des sciences de l'agriculture et de l'alimentation, Université Laval, Québec, Qc, Canada.
Deep 3D imaging of oocytes shows several difficulties. Their large size, spherical shape causes depth-dependent artefactual shadow in the middle, resulting from refractive index mismatches induced by turbid organelles and lipid droplets. These mismatches lead to optical aberrations, increasing the laser spot size at the confocal pinhole plan and causing significant attenuation of fluorescence intensity making difficult to clearly image fine structures such as the transzonal projections (TZPs) connecting cumulus cells and the oocyte.
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