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Article Abstract

A novel chiroptical spectrophotometer, Multichannel (MC)-circular dichroism (CD), which does not require a wavelength scan and provides artifact-free CD spectra in seconds, was developed by solving the incompatibility problem between data acquisition and modulation timescales. The design and instrumentation are compared with the Universal Chiroptical Spectrophotometer (UCS)-1, which can measure artifact-free CD spectra in the solid state. Enantiomeric single crystals composed of achiral components, α-Ni(H O) ・SO , and achiral films with substantial macroscopic anisotropies were measured on both MC-CD and UCS-1 and compared.

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http://dx.doi.org/10.1002/chir.23622DOI Listing

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A novel chiroptical spectrophotometer, Multichannel (MC)-circular dichroism (CD), which does not require a wavelength scan and provides artifact-free CD spectra in seconds, was developed by solving the incompatibility problem between data acquisition and modulation timescales. The design and instrumentation are compared with the Universal Chiroptical Spectrophotometer (UCS)-1, which can measure artifact-free CD spectra in the solid state. Enantiomeric single crystals composed of achiral components, α-Ni(H O) ・SO , and achiral films with substantial macroscopic anisotropies were measured on both MC-CD and UCS-1 and compared.

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Circularly polarized luminescence (CPL) is a fast growing research field as a complementary chiroptical spectroscopy alternative to the conventional circular dichroism or in the quest of devices producing circularly polarized light for different applications. Because chiroptical signals are generally lower than 0.1%, conventional chiral spectroscopies rely on polarization time modulation requiring step-by-step wavelength scanning and a long acquisition time.

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Circularly polarised light (CPL) interacting with interstellar organic molecules might have imparted chiral bias and hence preluded prebiotic evolution of biomolecular homochirality. The L-enrichment of extra-terrestrial amino acids in meteorites, as opposed to no detectable excess in monocarboxylic acids and amines, has previously been attributed to their intrinsic interaction with stellar CPL revealed by substantial differences in their chiroptical signals. Recent analyses of meteoritic hydroxycarboxylic acids (HCAs) - potential co-building blocks of ancestral proto-peptides - indicated a chiral bias toward the L-enantiomer of lactic acid.

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Chiroptical spectrophotometer and analytical method for optically anisotropic samples.

Rev Sci Instrum

December 2020

Department of Integrated Science and Technology, Faculty of Science and Technology, Oita University, Dannoharu, 700, Oita City 870-1192, Japan.

A new dual-polarization-modulated comprehensive chiroptical spectrophotometer (D-CCS) was successfully developed for recording artifact-free chiroptical circular dichroism (CD) and circularly polarized luminescence (CPL) spectra of optically anisotropic samples on the basis of the Stokes-Mueller matrix approach. The D-CCS includes an additional second photoelastic modulator (PEM) set in front of the sample and a second PEM controller being driven independently of the first PEM driver, which are essential for obtaining artifact-free chiroptical signals of optically anisotropic samples containing non-chiral signals, i.e.

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