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Objectives: Building upon our recently developed conceptual definition of oral frailty (the age-related functional decline of orofacial structures), this e-Delphi study aims to develop an operational definition of oral frailty by identifying its components.
Methods: We used a modified e-Delphi study to reach a consensus among international experts on the components of oral frailty. Twelve out of fifteen invited experts in the field of gerodontology participated. Experts responded to three rounds of an online 5-point scale questionnaire of components to be included or excluded from the operational definition of oral frailty. After each round, scores and rationales were shared with all experts, after which they could revise their position. A consensus was reached when at least 70% of the experts agreed on whether or not a component should be included in the operational definition of oral frailty.
Results: The experts achieved a high level of agreement (80 - 100%) on including eight components of oral frailty and excluding nineteen. The operational definition of oral frailty should include the following components: 1) difficulty eating hard or tough foods, 2) inability to chew all types of foods, 3) decreased ability to swallow solid foods, 4) decreased ability to swallow liquids, 5) overall poor swallowing function, 6) impaired tongue movement, 7) speech or phonatory disorders, and 8) hyposalivation or xerostomia.
Conclusion: This e-Delphi study provided eight components that make up the operational definition of oral frailty. These components are the foundation for the next stage, which involves developing an oral frailty assessment tool.
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http://dx.doi.org/10.1016/j.archger.2023.105181 | DOI Listing |
JAMA Netw Open
September 2025
Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock.
Importance: Patients with kidney failure (KF) receiving long-term dialysis have increased incidence of atrial fibrillation (AF). Patients with KF and AF have increased risk of stroke, death, and bleeding compared with age-matched cohorts. In KF, the use of oral anticoagulants (OACs) increases hemorrhage risk, offsetting potential benefits and making left atrial appendage occlusion (LAAO) a potentially promising solution for risk reduction in AF.
View Article and Find Full Text PDFJ Oral Rehabil
September 2025
Department of Prosthodontics, Dental School, National and Kapodistrian University of Athens, Athens, Greece.
Background: Although oral diseases and frailty can be met earlier in life, there is limited information on their association across the lifespan.
Objectives: To scope for the association of oral factors with physical frailty in Greek community-dwelling adults.
Methods: Participants were over 18 years of age with ≥ 20 natural teeth, ≥ 10 occlusal contacts, and no removable dentures.
Arch Gerontol Geriatr
August 2025
Institute of Gerontology, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, Japan; Institute for Future Initiatives, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, Japan. Electronic address:
A frailty checkup program (FC), a community-based frailty prevention initiative led by trained senior volunteers (FC supporters), has been implemented in over 100 municipalities in Japan. Participants create individual result sheets by marking blue signals for positive responses and red signals for negative responses. This cohort study aimed to examine the association between FC results and the risk of incident disability and mortality among community-dwelling older adults.
View Article and Find Full Text PDFNutr J
September 2025
Department of Geriatric, The First Hospital of China Medical University, No. 155 Nanjing North Street, Heping Ward, Shenyang, 110001, China.
Objective: This study analyzed data from the US population to examine how oral microbiome diversity and diet quality individually and synergistically affect frailty.
Methods: This study included 6,283 participants aged 20 years or older from the 2009-2010 and 2011-2012 NHANES cycles. A frailty index (FI) consisting of 36 items was developed, with items related to nutritional status excluded.
Eur J Vasc Endovasc Surg
September 2025
Department of Surgery, Division of Vascular Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:
Objective: Despite the growing number of vascular interventions performed in elderly patients, the functional outcomes regarding frailty remain unclear. This study aimed to evaluate and compare the short term functional outcomes in pre-operative frail vs. non-frail patients following open vs.
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