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http://dx.doi.org/10.1038/s41586-023-06355-3 | DOI Listing |
Acta Parasitol
September 2025
Région du Centre, Université Joseph Ki-Zerbo, Rue Thomas Sankara, O3 BP 7021, Ouagadougou, Burkina Faso.
Introduction: The objective of the World Health Organization is to achieve the interruption of human African trypanosomiasis (HAT) transmission by 2030.
Methods: This review aims to update knowledge on HAT, through a synthesis on the epidemiology, diagnostic tools and drugs of HAT.
Results: From 1960 to 2024 approximately 132,063 cases of HAT have been reported across Africa.
Clin J Am Soc Nephrol
September 2025
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL.
For many years, the vascular access guidelines recommended placement of arteriovenous fistulas (AVFs) in preference to arteriovenous grafts (AVGs) because AVFs had superior long-term patency, required fewer interventions to maintain patency, and were associated with lower costs of vascular access management. However, subsequent research has questioned the "Fistula First strategy" (placing an AVF whenever the vascular anatomy is suitable). First, AVF non-maturation is substantial (30-40%), and even higher among women, older patients and those with peripheral vascular disease.
View Article and Find Full Text PDFCochrane Database Syst Rev
September 2025
Division of Gastroenterology, Hepatology, and Nutrition, SickKids Research Institute and SickKids Learning Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Background: Training in endoscopy has traditionally been based upon an apprenticeship model, where novices develop their skills on real patients under the supervision of experienced endoscopists. In an effort to prioritise patient safety, simulation training has emerged as a means to allow novices to practice in a risk-free environment. This is the second update of the review, which was first published in 2012 and updated in 2018.
View Article and Find Full Text PDFFront Psychiatry
August 2025
TransLab Research Group, Department of Medical Sciences, University of Girona, Girona, Spain.
Introduction: Clinical practice guidelines (CPGs) have several limitations, namely: obsolescence, lack of personalization, and insufficient patient participation. These factors may contribute to suboptimal treatment recommendation compliance and poorer clinical outcomes. APPRAISE-RS is an adaptation of the GRADE heuristic designed to generate CPG-like treatment recommendations that are automated, updated, personalized, participatory, and explanatory using a symbolic AI approach.
View Article and Find Full Text PDF