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Objective: This study examines the factors associated with persistent, multi-year, and frequent emergency department (ED) use among children and young adults.
Methods: We conducted a retrospective secondary analysis using the 2012-2017 Healthcare Cost and Utilization Project State Emergency Department Databases for children and young adults aged 0-19 who visited any ED in Florida, Massachusetts, and New York. We estimated the association between persistent frequent ED use and individuals' characteristics using multivariable logistic regression models.
Results: Among 1.3 million patients with 1.8 million ED visits in 2012, 2.9% (37,558) exhibited frequent ED use (≥4 visits in 2012) and accounted for 10.2% (181,138) of all ED visits. Longitudinal follow-up of frequent ED users indicated that 15.4% (5770) remained frequent users periodically over the next 1 or 2 years, while 2.2% (831) exhibited persistent frequent use over the next 3-5 years. Over the 6-year study period, persistent frequent users had 31,551 ED visits at an average of 38.0 (standard deviation = 16.2) visits. Persistent frequent ED use was associated with higher intensity of ED use in 2012, public health insurance coverage, inconsistent health insurance coverage over time, residence in non-metropolitan and lower-income areas, multimorbidity, and more ED visits for less medically urgent conditions.
Conclusions: Clinicians and policymakers should consider the diverse characteristics and needs of pediatric persistent frequent ED users compared to broader definitions of frequent users when designing and implementing interventions to improve health outcomes and contain ED visit costs.
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http://dx.doi.org/10.1016/j.acap.2023.08.021 | DOI Listing |
J Pediatric Infect Dis Soc
September 2025
Infectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
Background: Critically ill pediatric patients admitted to the PICU are highly vulnerable to infections, including invasive fungal diseases and antifungal agents are frequently prescribed. Little is known about antifungal usage in PICUs across Europe.
Methods: A multinational 3-month weekly point-prevalence study for measuring antifungal drug use was organized.
Crit Rev Microbiol
September 2025
Chemistry Department, SUNY College of Environmental Science and Forestry, Syracuse, NY, USA.
The metalloid tellurium (Te) is toxic to bacteria; however, the element is also extremely rare. Thus, most bacteria will never encounter Te in their environment. Nonetheless significant research has been performed on bacterial Te resistance because of the medical applications of the element.
View Article and Find Full Text PDFConserv Biol
September 2025
Alfred Toepfer Academy for Nature Conservation, Schneverdingen, Germany.
The importance of social science to address the human dimensions of natural resource management is increasingly recognized in the conservation field, yet the application of associated concepts, theories, methods, and data remains underrepresented in parts of Europe. Common barriers and gaps, persistent over decades, including institutional constraints, work environment, different cultures and languages between natural and social science disciplines, lack of qualified personnel, and an accessible professional community, are often cited as underlying and driving factors. To better understand, contextualize, and inform solutions for wider use of social science, we analyzed interactions with conservation researchers and practitioners across a series of organized events from 2018 to 2023 (e.
View Article and Find Full Text PDFOnco Targets Ther
September 2025
State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Science, Inner Mongolia University, Hohhot, 010021, People's Republic of China.
Background: Insulinoma, the most common type of pancreatic endocrine tumor, frequently induces hypoglycemia due to persistent hyperinsulinemia. Although Mi-Lnc70 expression progressively increases during pancreatic maturation in mice, the biological role of Mi-Lnc70 in pancreatic β cells remains elusive.
Aim: This study was designed to investigate the role of LncRNA-Mi-Lnc70 in the mouse pancreatic β-cell line MIN6.
Clin Teach
October 2025
Warwick Medical School, Coventry, UK.
Background: Prescribing is a high-stakes clinical task where newly qualified doctors frequently report low confidence, with national data highlighting persistent error rates. Medical schools face logistical and staffing barriers in delivering high-quality, simulation-based prescribing education. Peer-led, interprofessional teaching, particularly by pharmacists, may offer a scalable solution in this context.
View Article and Find Full Text PDF