Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: To compare the outcomes of dichorionic triamniotic (DCTA) triplets who underwent fetal reduction (FR) to singletons or twins with those managed expectantly.
Methods: We conducted a retrospective study of DCTA triplets with three living fetuses at 11-14 weeks over a 7-year period. Pregnancy outcomes were compared following different management strategies.
Results: Of 108 included patients, 22 underwent expectant management (EM), 28 were reduced to dichorionic diamniotic twins, and 58 to singletons. The median gestational age at birth for EM, FR to twins, and singletons was 33.1 weeks, 37.0 weeks, and 38.6 weeks, respectively (P < 0.001). Prematurity before 37 and 34 weeks was less common following FR to singletons and twins than in ongoing triplets (18.9%, 46.2% and 90.5%, P < 0.001; 13.2%, 26.9% and 57.1%, P < 0.001). Neonatal birth weight was higher in triplets reduced to singletons and twins compared with EM cases (3140g, 2315g, and 1860g, P < 0.001). However, rates of miscarriage, pregnancies with ≥1 survivor, maternal complications, and adverse neonatal outcomes were comparable among the three groups.
Conclusions: In our experience, FR in DCTA triplets could reduce prematurity risk compared to EM, but it confers no survival advantage. Fetal reduction to singletons may result in more favorable outcomes than those reduced to dichorionic twins.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/pd.6437 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Collagen-elastin dermal scaffolds enhance tissue regeneration and reduce scarring in preclinical models.
Mater Today Bio
October 2025
Radboud University Medical Center, Research Institute for Medical Innovation, Department of Medical BioSciences, Geert Grooteplein 28, 6525 GA, Nijmegen, the Netherlands.
Severe scarring is an inevitable consequence of large full-thickness skin wounds, often leading to long-term complications that affect patients' well-being and necessitate extended medical interventions. While autologous split-thickness skin grafts remain the clinical standard for wound treatment, they frequently result in contractures, excessive scarring, and the need for additional corrective procedures. To address these challenges, bioengineered skin substitutes capable of promoting efficient healing while reducing complications are highly desirable.
View Article and Find Full Text PDFSecular trends in the prevalence of small vulnerable newborns in Japan, 1997-2021.
J Epidemiol
September 2025
Department of Social Medicine, National Center for Child Health and Development.
BackgroundIn 2023, a collaborative UNICEF-WHO group introduced the concept of small vulnerable newborns (SVNs) to improve the identification of newborns at increased risk of adverse outcomes and to guide more effective preventive strategies. However, global data on the prevalence of SVNs remains scarce. This study aimed to examine secular trends in the prevalence of SVNs and their three subgroups, namely term small for gestational age (SGA), preterm SGA, and preterm non-SGA, in the Japanese population.
View Article and Find Full Text PDFA Practical Prenatal Ultrasound Classification System for Lower Limb Anomalies-PRELLIM Classification.
Prenat Diagn
September 2025
Department of Obstetrics and Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Objective: To address the current lack of a prenatal classification system for fetal lower limb anomalies, we developed and evaluated the PRELLIM (PREnatal Lower LIMb impairment) classification.
Method: A systematic literature review was conducted to identify existing classifications. Based on sonographic features, we developed the PRELLIM classification and applied it to a retrospective cohort of fetuses with isolated lower limb anomalies assessed between 2007 and 2024 at Amsterdam UMC's fetal medicine unit.
Cryopreservation of chicken and duck tracheal rings and precision-cut lung slices: A promising tool for the rapid characterization of avian influenza viruses.
J Virol Methods
September 2025
Department of Virology, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, PD, Italy. Electronic address:
Since its emergence in 1996, highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 lineage have diversified into multiple clades, culminating in the 2020-2021 global panzootic caused by H5N1 viruses of the clade 2.3.4.
View Article and Find Full Text PDFMethod for fetal ultrasound image classification using pseudo-labelling with PCA-KMeans and an attention-augmented MobileNet-LSTM model.
MethodsX
December 2025
Symbiosis Institute of Technology, Pune Campus, Symbiosis International (Deemed University), Pune, India.
Accurate classification of fetal ultrasound images is critical for early diagnosis, yet remains challenging due to limited labeled data and high inter-class variability. This study presents a robust deep learning framework that combines a MobileNet backbone with multi-head self-attention and LSTM layers to enhance feature learning and temporal context. To address data scarcity and imbalance, unsupervised clustering was employed using Principal Component Analysis (PCA) for dimensionality reduction and K-means (k=4) for pseudo-label generation.
View Article and Find Full Text PDF