Angioedema-like contact dermatitis due to methylisothiazolinone in a mouthwash.

Contact Dermatitis

Section of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Published: November 2023


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http://dx.doi.org/10.1111/cod.14392DOI Listing

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Article Synopsis
  • Octylisothiazolinone (OIT) is a biocide used in leather products, raising concerns about allergic reactions, particularly in headphones.
  • A study reported cases of allergic contact dermatitis (ACD) in patients linked to headphones containing OIT, confirming its strong allergic potential through patch testing and chemical analysis.
  • The findings suggest that OIT is a significant sensitizer and highlight the need for safer use guidelines and improved product labeling in the leather industry to protect consumers.
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Disfiguring angioedema-like airborne dermatitis from methylisothiazolinone in paints: About time to regulate?

Contact Dermatitis

November 2021

Department of Dermatology, University Hospital Antwerp (UZA) and Research group Immunology, Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium.

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