Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369585 | PMC |
| http://dx.doi.org/10.1016/j.opresp.2023.100241 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Platypnea-orthodeoxia syndrome in bilateral SARS-CoV-2 pneumonia: An emerging and underdiagnosed clinical entity. Presentation of a case].
Rev Esp Geriatr Gerontol
August 2025
Facultativo Especialista de Área en Geriatría, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
Platypnea-Orthodeoxia Syndrome Due to Sinus Venosus Atrial Septal Defect With Partial Anomalous Pulmonary Venous Return.
JACC Case Rep
August 2025
Division of Cardiology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:
Background: Platypnea-orthodeoxia syndrome is a rare cause of positional hypoxia resulting from right-to-left shunting, often associated with intracardiac defects and abnormal venous return.
Case Summary: A 68-year-old woman with progressive hypoxia presented with positional desaturation and was found to have a superior sinus venosus atrial septal defect with partial anomalous pulmonary venous return. After diagnosis via bubble echocardiography and cardiac magnetic resonance imaging, successful transcatheter closure was performed with resolution of hypoxia.
Platypnea-orthodeoxia syndrome is a rare disorder characterized by dyspnea (platypnea) and arterial desaturation (orthodeoxia) in the upright position, with symptom relief upon lying down. This syndrome is commonly associated with cardiac anomalies, particularly patent foramen ovale (PFO), where increased right atrial pressure facilitates right-to-left shunting, leading to hypoxemia. Other associated conditions include cirrhosis, pericardial effusion, and pneumonectomy.
View Article and Find Full Text PDFPercutaneous closure of patent foramen ovale in patients with platypnea-orthodeoxia syndrome: an Italian multicenter experience.
Minerva Cardiol Angiol
July 2025
Unit of Structural Interventional Cardiology, Careggi University Hospital, Florence, Italy.
Background: Patent foramen ovale (PFO)-associated platypnea-orthodeoxia syndrome (POS) is a rare and often underdiagnosed condition characterized by hypoxemia refractory to oxygen therapy and paroxysmal dyspnea in the upright position, with normal arterial oxygen saturation (SO
Methods: This retrospective multicenter study included patients diagnosed with POS undergoing percutaneous PFO closure between 2020 and 2024 across eight tertiary Italian hospitals.
Atrial Septal Defect With Right-to-Left Shunt Without Pulmonary Hypertension: Diagnosis Through Multimodality Imaging.
JACC Case Rep
June 2025
Department of Cardiology, Yokohama City University, Yokohama, Japan.
Background: Four-dimensional flow magnetic resonance imaging (MRI) enhances the evaluation of complex cardiovascular diseases. We used MRI and advanced imaging modalities to assess a right-to-left shunt through an atrial septal defect without pulmonary hypertension (PH).
Case Summary: An 84-year-old woman with persistent hypoxemia was found to have a significant right-to-left shunt without PH.