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http://dx.doi.org/10.1038/d41573-023-00119-4 | DOI Listing |
Eur J Orthop Surg Traumatol
September 2025
Human Anatomy Teaching and Research Section, School of Basic Medicine, Inner Mongolia Medical University, Hohhot, China.
Objective: Reveal the changing rule of the positional relationship between the uncinate process of cervical spine and vertebral artery by measuring the relevant parameters between the uncinate process of cervical spine and vertebral artery in different age groups.
Methods: A retrospective study was conducted on 1240 cases of cervical spine imaging data from 2018 to 2021 in the Radiology Department of the Affiliated Hospital of Inner Mongolia Medical University. The distance between the uncinate process superior ridge and vertebral artery and the maximum of pedicle transverse angle, the minimum of pedicle transverse angle, the range of pedicle transverse angle and the pedicle width were measured according to age groups.
Future Sci OA
December 2025
Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Background: Smoking induces inflammation in the heart and intima layer of blood vessels by activating nuclear factor kappa B, which controls the transcription of immunoglobulin free light chain (FLC)-κ. FLC levels are indicative of higher mortality in the overall population and poorer prognoses in cardiovascular diseases. This study aimed to analyze the effect of smoking cessation (SC) on the levels of FLCs and markers of inflammation and heart failure.
View Article and Find Full Text PDFMol Pharm
September 2025
Johnson & Johnson, Translational PK/PD & Investigational Toxicology, Spring House, Pennsylvania 19002, United States.
Human intestinal permeability is a key determinant of the oral fraction absorbed () of active pharmaceutical ingredients (APIs). This study evaluated the ability of an in-house canine Mdr1 (cMdr1) knockout (KO) Madin-Darby Canine Kidney (MDCK) cell line to correlate apparent permeability () with human small intestinal permeability (). values of 16 reference compounds with high, medium, or low permeabilities were measured in the in-house cMdr1 KO MDCK protocol under pH gradient (6.
View Article and Find Full Text PDFInjections have been linked to feline sarcomas (feline injection-site sarcoma; FISS) and cutaneous lymphomas (cutaneous lymphoma at injection site; CLIS). Both tumors often exhibit lymphoplasmacytic inflammation ascribed to injected immunogenic material. CLIS is hypothesized to emerge from transformation and clonal expansion of lymphoid cells following persistent immune stimulation with feline leukemia virus (FeLV) reactivation and transformation.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
The aluminum electrolysis industry generates massive greenhouse gas emissions dominated by CO and perfluorocarbons (PFCs, CF/CF), presenting dual challenges of climate impact and resource waste. Here, we report a robust nickel-based metal-organic framework (SIFSIX-3-Ni) featuring confined square channels (3.55 Å) that achieves the molecular-sieving separation of CO from CF/CF mixtures.
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