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Introduction: The discordance in the diagnosis of osteoporosis is characterized by the variation in bone mineral density measurements at different skeletal sites. The presence of discordance significantly alters the treatment plan as different treatment is required for different skeletal sites. The aim of this study was to find out the prevalence of hip-spine discordance in bone mineral densities in patients undergoing dual-energy x-ray absorptiometry scans for suspected osteoporosis.
Methods: A descriptive cross-sectional study was conducted among patients undergoing dual-energy x-ray absorptiometry scans from 1 December 2020 to 30 October 2022. Ethical approval was taken from the Institutional Review Committee (Reference number: IRC-2020-11-18-08). Patients undergoing dual-energy x-ray absorptiometry scans for suspected osteoporosis were included. Patients aged less than 50 years, already diagnosed and under treatment for osteoporosis, and incomplete information about T-scores of hips and spine were excluded. Convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated.
Results: Among 1028 patients, 602 (58.56%) (55.55-61.57, 95% Confidence Interval) had discordance in hip and spine bone mineral densities. The majority of them, 570 (94.68%) were female and 32 (5.71%) were male. Major discordance was observed in 101 (16.77%) patients and minor discordance was observed in 501 (83.22%) patients.
Conclusions: The prevalence of discordance in hip and spine bone mineral densities in patients undergoing dual-energy x-ray absorptiometry scans was higher than that reported in other similar studies done in similar settings.
Keywords: bone density; osteoporosis; prevalence.
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http://dx.doi.org/10.31729/jnma.7951 | DOI Listing |
Am J Hematol
September 2025
Calcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Division of Endocrinology, American University of Beirut Medical Center, Beirut, Lebanon.
Ann Gastroenterol Surg
September 2025
Division of Gastrointestinal Surgery, Department of Surgery Jikei University School of Medicine Tokyo Japan.
Background: Our previous study suggested that low bone mineral density (BMD), known as osteopenia, was a poor prognostic factor in patients who underwent esophagectomy for esophageal cancer (EC).Meanwhile, the association between BMD reduction during neoadjuvant chemotherapy (NAC) and the worse prognosis remains unknown, although esophagectomy after NAC is the first option for the treatment of advanced esophageal squamous cell carcinoma (ESCC). Therefore, this study intended to investigate the prognostic impact of BMD reduction during NAC.
View Article and Find Full Text PDFInt J Implant Dent
September 2025
Department of Periodontology, Center for Biomedical Education and Research (ZBAF), School of Dentistry, Faculty of Health, Witten/Herdecke University, Witten, Germany.
Background: Guided bone regeneration (GBR) relies on biocompatible membranes to support osteogenesis. 1,4-butanediol diglycidyl ether (BDDE)-crosslinked hyaluronic acid (xHyA) has shown promise in enhancing bone regeneration, yet its mechanisms remain unclear.
Objective: This study evaluates the osteogenic effects of xHyA-functionalized native pericardium collagen membrane (NPCM) and ribose-crosslinked collagen membrane (RCCM) using an airlift culture model with SaOS-2 cells.
Arch Osteoporos
September 2025
Internal Medicine Service, Río Hortega University Hospital, Valladolid, Spain.
Unlabelled: This retrospective cohort study analysed a total of 344 patients from the OSTEOMED registry with matched baseline and follow-up DXA data, finding that comorbidities such as nephrolithiasis, hypertension or coronary heart disease may influence the response to prescribed anti-osteoporotic treatment.
Purpose: To determine: 1) comorbidities associated with reduced bone mineral density (BMD), T-score and Z-score at the lumbar spine (L1 to L4 vertebrae), femoral neck and total hip; and 2) the role of multimorbidity (≥ 2 comorbidities) in reduced BMD, T-score and Z-score at the lumbar spine, femoral neck and total hip.
Methods: Retrospective cohort study analyzing patients [319 females (92.
Osteoporos Int
September 2025
Clinical Epidemiology Research Unit, Hospital Infantil de Mexico "Federico Gomez", Mexico City, Mexico.
Purpose: Conduct an overview of systematic reviews of the current fracture risk prediction tools in use.
Material And Methods: We included systematic reviews (SRs) that assessed the predictive ability of any tool, score, algorithm, or other instrument for fracture risk. The primary outcome measure was the area under the curve (AUC) representing predicted fracture risk within a specified timeframe obtained from receiver operating characteristic (ROC) analysis.