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http://dx.doi.org/10.1016/j.anpede.2023.06.011 | DOI Listing |
JAAD Case Rep
September 2025
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
Mol Syndromol
August 2025
Department of Medical Genetics, School of Medicine (KUSoM), Koç University, Istanbul, Turkey.
Introduction: Lipoid proteinosis (LP), a rare autosomal recessive disorder typified by generalized thickening of the skin, mucosa, and certain viscera, is associated with pathogenic variants. Skin lesions like beaded eyelid papules, acneiform scars, wavy, yellow papules and nodules typically appear in early childhood. Some patients may exhibit neurological abnormalities like temporal lobe or hippocampi-amygdala complex calcification, epilepsy, and neuropsychiatric abnormalities.
View Article and Find Full Text PDFJ Am Acad Dermatol
June 2025
Department of Dermatology, Duke University School of Medicine, Durham, NC. Electronic address:
Mast cells are tissue-resident immune cells which secrete numerous and varied immune mediators in response to a myriad of activation pathways and play an important physiological function in immunity, homeostasis, tissue repair, and nervous system regulation. New understandings in activation and signaling have led to new drug targets. Mastocytosis is a hematologic clonal neoplasm resulting from aberrant proliferation, maturation, and infiltration of mast cells.
View Article and Find Full Text PDFClin Cosmet Investig Dermatol
June 2025
Department of Dermatology, Chengdu Pidu District Hospital of Traditional Chinese Medicine, Pidu, Chengdu, People's Republic of China.
Introduction: Yellow urticaria (YU) is a rare variant of urticaria characterized by a transient yellow rash. It usually occurs at patients with hyperbilirubinemia. In clinic, the vasodilation and extravasation associated with urticaria facilitate the precipitation of bilirubin within the elastin fibers of the cutaneous tissue, which consequently leads to the emergence of atypical yellow papules and plaques.
View Article and Find Full Text PDFCase Rep Dermatol Med
June 2025
Department of Dermatology/Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Xanthelasma palpebrarum (XP) is a benign condition of the eyelid skin, characterized by the appearance of well-defined, bilateral, yellow-colored papules or plaques in the periorbital area. Although patients often seek dermatological consultation for cosmetic reasons, the associated medical implications, especially in younger individuals, hold significant medical importance. XP can be treated through various methods such as surgical removal, trichloroacetic acid (TCA) 70% application, cryotherapy, and laser procedures.
View Article and Find Full Text PDF