Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis.

Front Cardiovasc Med

Department of Internal Medicine and Translational Cardiovascular Research Center, College of Medicine, University of Arizona, Phoenix, AZ, United States.

Published: April 2023


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309071PMC
http://dx.doi.org/10.3389/fcvm.2023.1120487DOI Listing

Publication Analysis

Top Keywords

falling corin
4
corin anp
4
anp activity
4
activity levels
4
levels accelerate
4
accelerate development
4
development heart
4
heart failure
4
failure cardiac
4
cardiac fibrosis
4

Similar Publications

Introduction: The optimal treatment for postoperative Vancouver AG fractures has not been established. This study is a case series investigating the outcomes of patients from a single, academic tertiary referral center with conservative management of postoperative, traumatic periprosthetic fractures, specifically Vancouver type AG fractures.

Methods: This study was a retrospective review of 225 patients diagnosed with periprosthetic fracture at an academic, tertiary referral center from January 2007 to June 2023.

View Article and Find Full Text PDF

Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis.

Front Cardiovasc Med

April 2023

Department of Internal Medicine and Translational Cardiovascular Research Center, College of Medicine, University of Arizona, Phoenix, AZ, United States.

View Article and Find Full Text PDF

Plasma corin decreases after coronary artery bypass graft surgery and is associated with postoperative heart failure: a pilot study.

J Cardiothorac Vasc Anesth

April 2015

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, TX.

Objective: Corin is a natriuretic peptide-converting enzyme that cleaves precursor pro-B-type natriuretic peptide to active B-type natriuretic peptide (BNP) (diuretic, natriuretic, and vasodilatory properties). Increased plasma BNP is a known diagnostic and prognostic heart failure (HF) biomarker in ambulatory and surgical patients. Recent studies indicate that plasma corin is decreased significantly in chronic HF patients, yet perioperative plasma corin concentrations have not been assessed in cardiac surgical patients.

View Article and Find Full Text PDF