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http://dx.doi.org/10.1097/BPO.0000000000002461 | DOI Listing |
Curr Opin Neurol
October 2025
Neuromuscular Diseases Unit, Department of Neurology, IR SANT PAU, Hospital de la Santa Creu i Sant Pau, CIBERER, Barcelona, Spain.
Purpose Of Review: Autoimmune nodopathies (AN) are a recognized distinct group of immune-mediated peripheral neuropathies with unique immunopathological features and therapeutic implications. This review synthesizes recent advances in their pathogenesis, diagnosis, and management, which have refined their clinical classification and informed targeted treatment strategies.
Recent Findings: AN are characterized by autoantibodies targeting surface proteins in the nodal-paranodal area (anti-contactin-1, anti-contactin-associated protein 1, anti-neurofascin-155, anti-pan-neurofascin), predominantly of IgG4 subclass.
Neurologia (Engl Ed)
September 2025
Unidad de ELA-Neuromuscular, Servicio de Neurología, Hospital General Universitario Gregorio Marañón, Madrid, Spain; IiSGM, Instituto de Investigación Sanitaria Gregorio Marañón.
Objectives: To describe the main features and the clinical management of a cohort of patients with immune-mediated necrotizing myopathy (IMNM).
Methods: We conducted an observational, monocentric, retrospective study of IMNM patients diagnosed in the Neuromuscular Unit of a tertiary hospital in Madrid (Spain) between 2013 and 2021.
Results: Sixteen IMNM cases were diagnosed, with a median age of 71.
Percept Mot Skills
September 2025
Department of Physical Education and Health, Higher Institute of Physical Education, University of the Republic, Montevideo, Uruguay.
Tabata-based High-Intensity Functional Training (HIFT) elicits hybrid adaptations in both cardiorespiratory and neuromuscular systems. However, its high Rating of Perceived Exertion (RPE) may limit its feasibility. This study aimed to analyze the acute physiological and psychological responses to a modified low-volume Tabata-based HIFT incorporating short efforts, with a focus on potential differences between sexes.
View Article and Find Full Text PDFFront Physiol
August 2025
Department of Physical Education and Sports Faculty of Sport Science, Afyon Kocatepe University, Afyonkarahisar, Türkiye.
This study examined the effects of the time of day on anaerobic performance and blood lactate levels in 20 trained male athletes with intermediate type (IT) and close to evening type (CET) chronotypes. The athletes completed vertical jump and repeated sprint ability (6 × 20 m) tests at three different times (07:00-08:00 h, 13:00-14:00 h, and 18:00-19:00 h). Blood lactate levels were measured at baseline, post-RSA (3 min), and post-RSA (33 min).
View Article and Find Full Text PDFInt J Sports Physiol Perform
September 2025
Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, Italy.
Purpose: Rapid force production relies upon neuromuscular mechanisms differing from those underlying maximal strength. In chronically strength-trained individuals, specific adaptations in rapid force variables (RFVs)-both absolute and normalized to maximal force capacity-following resistance training with ballistic versus controlled contractions remain underexplored. Therefore, we examined whether improvements in maximal propulsive power (MaxPP) coincide with RFV responses, specifically, rate of force development (RFD) and impulse.
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