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This paper carries out probabilistic approach to quantify the benefit-risk analysis for foods (BRAFO) of omega-3 polyunsaturated fatty acid and methylmercury (MeHg) for the people who eat the mercury-contaminated fish in Taiwan. We applied the hazard quotient (HQ) model to assess the risk of developmental neuropsychological impairment effect and the desirable dose index (DI) model to quantify the health benefits. Besides, we also applied the disability adjusted life years (DALY) model to assess the number of years lost by incidence of affected infants' intelligence quotient (IQ) and coronary heart disease (CHD) or Stroke for adult. The results of this study show that although the risk of cod and scad are higher, Taiwan residents do not need to reduce intake rate based on benefit considerations. Furthermore, according to the benefits of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), this study suggests that more intake of saury and salmon.
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http://dx.doi.org/10.1016/j.marpolbul.2023.115179 | DOI Listing |
BMC Endocr Disord
September 2025
Internal Medicine Department, Faculty of Medicine, Beni-Suef University, Beni-Suef City, 62514, Egypt.
Background: Thyroid nodules (TNs) are frequent and often benign. Accurately differentiating between benign and malignant nodules is crucial for proper management. This research aims to use ultrasonography to examine TNs and identify possible risk factors in order to improve patient outcomes and diagnostic accuracy.
View Article and Find Full Text PDFEnviron Geochem Health
September 2025
Environmental Hydrology Division, National Institute of Hydrology, Roorkee, 247667, India.
Radon (Rn) is a naturally occurring radioactive gas produced by the decay of uranium-bearing minerals in rocks and soils. Long-term exposure to elevated radon levels in drinking water is associated with an increased risk of stomach and lung cancers. This study aims to assess the concentration of radon in groundwater and evaluate its potential health risks in six cancer-affected districts, i.
View Article and Find Full Text PDFObes Surg
September 2025
Department of General and Visceral Surgery, University Hospital Brandenburg an der Havel, Brandenburg an der Havel, Germany.
Background: Perioperative antibiotic prophylaxis (PAP) prior to laparoscopic gastric bypass surgery is still under debate due to a lack of high evidence. Thus, the study at hand aimed to find out whether this medication lowers the rate of postoperative complications or not.
Methods: In 2020, a retrospective analysis took place at Helios Hospital Berlin Buch, Germany.
Sci Rep
September 2025
College of First Clinical Medical, Shandong University of Traditional Chinese Medicine, Jinan, China.
Obstructive sleep apnea (OSA) is associated with metabolic disorders such as insulin resistance and liver fat accumulation. However, the specific mediating role of liver-related metabolic indicators in this association has not been fully studied. The purpose of this study was to investigate the relationship between Metabolic Score for Insulin Resistance (METS-IR) and OSA, focusing on the mediating effects of liver fat percentage (PLF) and hepatic steatosis index (HSI).
View Article and Find Full Text PDFCell Death Discov
September 2025
Department of Molecular Oncology, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Ado-trastuzumab is considered a standard treatment for patients with HER2+ metastatic breast cancer (mBC). Current clinical practices do not reliably predict therapeutic outcomes for patients who are refractory to therapy. Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression and therapeutic resistance, and the use of lncRNAs as tumor biomarkers is becoming more common in other diseases.
View Article and Find Full Text PDF