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Article Abstract

A visible-light-induced efficient methodology has been developed for the C-H selenylation of pyrazolo[1,5-]pyrimidine derivatives employing erythrosine B as the photocatalyst. This is the first report on the regioselective selenylation of pyrazolo[1,5-]pyrimidines. The efficiency of this methodology for the selenylation of different electron-rich heterocycles like pyrazole, indole, imidazo[1,2-]pyridine, imidazo[2,1-]thiazole, and 4-(phenylamino)-2-chromen-2-one has been also demonstrated. The exploration of erythrosine B as a photocatalyst with a simple and mild procedure, wide substrate scope, and practical applicability and the employment of eco-friendly energy, oxidant, and solvent are the attractive characteristics of this methodology.

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http://dx.doi.org/10.1021/acs.joc.3c00720DOI Listing

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