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Optical solitary waves (solitons) that interact in a nonlinear system can bind and form a structure similar to a molecule. The rich dynamics of this process have created a demand for rapid spectral characterization to deepen the understanding of soliton physics with many practical implications. Here, we demonstrate stroboscopic, two-photon imaging of soliton molecules (SM) with completely unsynchronized lasers, where the wavelength and bandwidth constraints are considerably eased compared to conventional imaging techniques. Two-photon detection enables the probe and tested oscillator to operate at completely different wavelengths, which permits mature near-infrared laser technology to be leveraged for rapid SM studies of emerging long-wavelength laser sources. As a demonstration, using a 1550 nm probe laser we image the behavior of soliton singlets across the 1800-2100 nm range, and capture the rich dynamics of evolving multiatomic SM. This technique may prove to be an essential, easy-to-implement diagnostic tool for detecting the presence of loosely-bound SM, which often remain unnoticed due to instrumental resolution or bandwidth limitations.
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http://dx.doi.org/10.1038/s41467-023-39045-9 | DOI Listing |
Neurochem Int
September 2025
Guangdong Provincial Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China; Advanced Medical Technology Center, the First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China; Key La
General anesthetics are essential in pediatric medicine, yet concerns persist regarding their potential neurotoxic effects on the developing brain. Whether transient synaptic disruptions caused by anesthesia lead to long-term deficits or are mitigated by endogenous plasticity remains unresolved. Here, we use longitudinal in vivo two-photon imaging in awake mice to investigate the structural and functional consequences of a single, clinically relevant exposure to sevoflurane at postnatal day 20.
View Article and Find Full Text PDFBioorg Chem
September 2025
Aix Marseille Univ., CNRS UMR 7325 Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), Campus de Luminy, 13288 Marseille cedex 09, France. Electronic address:
In the field of theranostics, triaminophenaziniums are promising molecules due to their intrinsic properties such as an absorbance beyond 500 nm associated with large molar extinction coefficients, high fluorescence quantum yields, as well as phototoxicity. This study explored how three triaminophenazinium salts relate in structure and activity, highlighting their potential as theranostic agents. The nature of the moiety in position 2 of the dyes was varied from H, to -CH or -Bu.
View Article and Find Full Text PDFJ Phys Chem A
September 2025
Department of Chemistry, Brown University, Providence, Rhode Island 02912, United States.
Chlorothiophenols are key precursors for polychlorinated dibenzothiophenes, which are a class of persistent organic pollutants environmentally, but little is known about their electronic and spectroscopic properties. We report a high-resolution spectroscopic investigation of the cryogenically cooled 2-chlorothiophenoxide (2-CTP) anion using photoelectron imaging, photodetachment spectroscopy, and resonant photoelectron spectroscopy. High-resolution photoelectron spectroscopy yields an accurate electron affinity of 21,005 ± 5 cm (2.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.
Understanding how molecular aggregation influences nonlinear optical properties is essential for advancing organic fluorophores in imaging, sensing, and photonic applications. However, the relationship between the molecular aggregation and the magnitude of nonlinear two-photon absorption cross-section remains underexplored. Here, we systematically investigate the aggregation-dependent two-photon absorption properties of the fluorophore TPAPhCN by tuning the degree of aggregation.
View Article and Find Full Text PDFNeuropharmacology
September 2025
Department of Life Sciences, Ben-Gurion University of the Negev, 84105, Beer Sheva, Israel; Zelman Center for Brain Science Research, Ben-Gurion University of the Negev, 84105, Beer Sheva, Israel. Electronic address:
Norepinephrine (NE) is a key neuromodulator in the brain with a wide range of functions. It regulates arousal, attention, and the brain's response to stress, enhancing alertness and prioritizing relevant stimuli. In the auditory domain, NE modulates neural processing and plasticity in the auditory cortex by adjusting excitatory-inhibitory balance, tuning curves, and signal-to-noise ratio.
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