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Aim: The present study aimed at evaluating the increase in the rate of tooth movement by increasing the number and frequency of micro-osteoperforations (MOPs).
Materials And Methods: The study was a single-center, split-mouth, randomized controlled trial. A total of 20 patients were included in the study who had fully erupted maxillary canines with class I molar canine relationship and a bimaxillary protrusion that required the removal of both maxillary and mandibular first premolars. Out of 80 samples, the experimental and controlled groups were randomly assigned. The experimental group received five MOPs in the extracted site of the first premolar before retraction, at 28th day and 56th day. The control group received no MOPs. The rate of tooth movement was measured on 28th, 56th, and 84th day on both the experimental and control sides.
Results: In maxillary dentition, the canine on the MOP side moved by 0.65 ± 0.21 mm, 0.74 ± 0.23 mm, and 0.87 ± 0.27 mm during 28th, 56th, and 84th day, respectively, whereas in control side the rate of tooth movement was 0.37 ± 0.09 mm, 0.43 ± 0.11 mm, and 0.47 ± 0.11 mm during 28th, 56th and 84th day, respectively, which was statistically significant (-value = 0.000). In mandibular dentition, the canine on the MOP site has moved by 0.57 ± 0.12 mm, 0.68 ± 0.21 mm, and 0.67 ± 0.10 mm during 28th, 56th, and 84th day, respectively, whereas in control side the rate of the tooth movement was 0.34 ± 0.08 mm, 0.40 ± 0.15 mm, and 0.40 ± 0.13 mm during 28th, 56th, and 84th day, respectively, which was statistically significant.
Conclusion: Micro-osteoperforations effectively increased the rate of tooth movement. Overall, MOPs increased the rate of canine retraction by 2-fold when compared with the control group.
Clinical Significance: Micro-osteoperforation is a proven methodology to increase the rate of tooth movement and decrease the treatment time. However, it is important to repeat the procedure during every activation to increase its effectiveness.
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http://dx.doi.org/10.5005/jp-journals-10024-3385 | DOI Listing |
J Neurol Neurosurg Psychiatry
September 2025
Department of Neurosciences and Behavioural Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Background: Biallelic variants lead to autosomal recessive Charcot-Marie-Tooth type 4C (CMT4C) which is typically demyelinating and associated with early-onset spinal deformities. Electrophysiology typically reveals a non-uniform conduction velocity (CV) slowing, a pattern traditionally linked to inflammatory neuropathies, potentially leading to diagnostic misinterpretation.
Objective And Methods: Clinical and neurophysiological data from 19 patients belonging to 16 unrelated families with confirmed CMT4C were retrospectively collected across six neuromuscular reference centres in Brazil.
Remimazolam is an ultrashort-acting benzodiazepine approved for procedural sedation in 2020 by the US Food and Drug Administration; however, dosing information originating from the US is limited. No existing literature details infusion rates of remimazolam delivered by manually adjusted infusion pumps. This case report describes the administration of manually infused remimazolam to an 86-year-old man for the surgical extraction of third molars under procedural sedation.
View Article and Find Full Text PDFJ Dent Educ
September 2025
Department of Prosthodontics, Oral Science Research Center, Yonsei University Dental College, Seoul, South Korea.
Purpose: Crown preparation is a fundamental procedure in restorative dentistry. This study aimed to evaluate quantitative and color-coded assessment of tooth reduction using various 3D-printed tooth reduction guides in comparison to conventional guiding methods during crown preparation.
Methods: Twelve prosthodontic residents from a single prosthodontic graduate program (first year: n = 6; second year: n = 6) participated in this IRB-approved study (Yonsei University Dental Hospital IRB 2-2024-0026).
Evid Based Dent
September 2025
Dental Core Trainee, Restorative Dentistry, Newcastle Dental Hospital, Cairo, Egypt.
A Commentary On: Mohamed M H, Abouauf E A, Mosallam R S. Clinical performance of class II MOD fiber reinforced resin composite restorations: an 18-month randomized controlled clinical trial. BMC Oral Health 2025;25: 159.
View Article and Find Full Text PDFKorean J Orthod
September 2025
Private Practice, Brisbane, Australia.
Objective: This study aimed to investigate the effects of low-nicotine cigarette smoke (CS) inhalation on orthodontic tooth movement (OTM) in rats.
Methods: Forty 4-week-old male Wistar rats, were randomly divided into four groups: three experimental and one control. Group 1 (control group) had dental impressions taken at week 9.