Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Peripheral nerve disease may lead to physical disability because of decreased muscle strength and/or loss of sensitivity in the dermatomes of affected peripheral nerves. Both human immunodeficiency virus (HIV)- and leprosy-affected patients can develop neurological damage; therefore, the coinfection of these diseases presents new challenges to the health care of these patients.
Aims And Objective: This study aimed to investigate the motor alterations of patients coinfected with HIV and leprosy and their relationship with clinical and anthropometric characteristics, compared with individuals with isolated diseases.
Materials And Methods: In this cross-sectional study, 90 individuals were divided equally into three groups: HIV/acquired immunodeficiency syndrome (AIDS) group, leprosy group and HIV/leprosy group. All individuals underwent an evaluation of muscle strength and upper limb endurance adjusted for the Brazilian standards, a palm print pressure test using a digital dynamometer and anthropometric measurements (weight, height and skin folds).
Results: The HIV/leprosy group had the highest mean body mass index, followed by the leprosy group and the HIV/AIDS group. Skinfolds were similar between the groups. Multiple linear regression, adjusted for sex and age, revealed the coinfection of HIV and leprosy as possible contributor to a worse prognosis of muscle function, highlighting the bilateral reduction in the levels of palm print compression strengths compared with isolated diseases (HIV and leprosy). High CD4 count and shorter antiretroviral therapy duration were associated with worse indices of muscle strength, such as gripping and resistance, in coinfected patients.
Conclusion: Patients coinfected with HIV and leprosy exhibited greater motor damage than those with isolated diseases. Thus, motor damage may be related to the sum of the neurological manifestations of the two morbidities.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238977 | PMC |
| http://dx.doi.org/10.4103/ijd.ijd_799_22 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Distribution of nontuberculous Mycobacteria among presumptive drug resistance tuberculosis patients from a ministry of health drug resistance surveillance program, in western Kenya.
J Clin Tuberc Other Mycobact Dis
December 2025
Maseno University, School of Public and Community Development, Department of Biomedical Sciences and Technology, Kisumu, Kenya.
Introduction: Nontuberculous Mycobacteria (NTM) species are emerging pathogens causing Pulmonary diseases with no definitive treatment. Molecular techniques enable characterization and drug resistance profiling, this study sought to determine NTM prevalence, circulating species, and distribution factors among presumptive multidrug-resistant tuberculosis (MDR-TB) patients in western Kenya.
Method: Sputum samples were collected between March through October 2022, and transported for testing at Kenya Medical Research Institute (KEMRI) TB laboratory, in Kisumu.
The Magnitude and Patterns of Acquired Drug Resistance Mutations and Circulating HIV-1 Subtypes in HIV Patients in Tanzania, a Systematic Review and Meta-Analysis.
Viruses
August 2025
Department of Internal Medicine, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences-Bugando, Mwanza P.O. Box 1464, Tanzania.
The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and patterns of DRMs in patients on ART in Tanzania. A systematic literature search was conducted in MEDLINE through PubMed, Embase, and CINAHL up to December 2024.
View Article and Find Full Text PDFThe Effect of Women's Empowerment on Unmet Needs for Family Planning in Tanzania: Analysis of 2022 Tanzania Demographic and Health Survey (TDHS).
BMC Public Health
August 2025
Social Entrepreneurship to Spur Health (SESH Global), University of North Carolina-Project China, Guangzhou, China.
Introduction: The role of women’s empowerment in reducing unmet needs for family planning (FP) has received limited attention, particularly in Tanzania. While empowerment may be key to addressing disparities in FP use, its impact on unmet FP needs remains underexplored. This study assessed the impact of women’s empowerment on unmet FP needs, using the Survey-based Women’s Empowerment (SWPER) Global Index as a measure of empowerment.
View Article and Find Full Text PDFBackground And Aims: Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Methods: Between February and March 2024, we searched PubMed, Web of Science, and Google Scholar databases and grey literature for NTDs articles published between January 1, 1980 and January 31, 2024.
Epidemiology and Outcomes of Pediatric Multidrug-resistant Tuberculosis in Namibia: A Retrospective Review of National Registry Data From 2013 to 2023.
Pediatr Infect Dis J
August 2025
Department of Human, Biological and Translational Medical Sciences, School of Medicine, University of Namibia, Windhoek, Namibia.
Background: Multidrug-resistant (MDR) and rifampin-resistant (RR) tuberculosis (TB) is challenging the national response to tuberculosis in Namibia. The recent introduction of Xpert MTB/RIF (Cepheid, Sunnyvale, CA) and the use of new and repurposed drugs have the potential to improve both management and outcomes.
Methods: Retrospective review of Namibian national registry data from 2013 to 2023 of children 0-14 years with MDR/RR-TB.