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http://dx.doi.org/10.1007/s11356-023-27966-3 | DOI Listing |
Top Magn Reson Imaging
October 2025
BIOSPACE LAB, Nesles-la-Vallée, France.
Aims: Cardiac tumors are aggressive and asymptomatic in early stages, causing late diagnosis and locoregional metastasis. Currently, the standard of care uses gadolinium-based contrast agents for MRI, and the associated hypersensitivity reactions are a significant concern, such as gadolinium deposition disease. In addition, the proximity of cardiac lesions closer to vital structures complicates surgical interventions.
View Article and Find Full Text PDFClin Chim Acta
July 2025
Department of Medical Biochemistry, Immunology and Toxicology, University Hospital of Wales, Cardiff, Wales, UK; School of Medicine, Cardiff University, Cardiff, Wales, UK. Electronic address:
Introduction: Accurate and rapid assessment of galactose-1-phosphate uridyl transferase (GALT) activity is critical for the diagnosis of Classical Galactosemia (CG). However, the performance of GALT assays is variable, and there is a lack of evidence to support best practices.
Materials And Methods: We established a rapid quantitative fluorometric GALT assay to evaluate the impact of blood collection-tubes, assay-composition, and sample storage conditions using whole blood (WB) and dried blood spot (DBS) specimens from control individuals, CG patients and individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Vet Clin Pathol
June 2025
School of Veterinary Medicine and Science, University of Nottingham, Leicestershire, UK.
Background: Previous studies have shown that veterinary in-clinic hematology analyzers may have analytical errors, but few studies have been found that attempt bias correction and look at the effect of this on the achievement of several quality goals and evaluation of analytical performance specifications.
Objectives: To design a comparative testing program for use by in-clinic laboratories with a variety of point-of-care (POC) analyzers and to evaluate the performance of in-clinic hematology analyzers compared to a reference analyzer. To determine whether the removal of bias from the in-clinic result can be used in preparation for the harmonization of the results with those of the reference laboratory.
Diagnostics (Basel)
July 2025
Institute of Laboratory Medicine, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
D-dimer determined in citrated plasma is a well-established and efficient biomarker, particularly for ruling out venous thromboembolism. In certain clinical settings, the availability of citrated plasma may pose challenges when not readily available. To address this issue, we investigated the feasibility of using ethylenediaminetetraacetic acid (EDTA) plasma as an alternative specimen for D-dimer measurement.
View Article and Find Full Text PDFMaterials (Basel)
June 2025
Department of Operative Dentistry, Institute of Medicine, Peoples' Friendship University of Russia Named after Patrice Lumumba (RUDN University), Miklukho-Maklaya Str. 6, 117198 Moscow, Russia.
The effect of root canal irrigants on the mechanical properties of dentin is crucial in endodontic treatment planning. While antiseptics such as sodium hypochlorite and EDTA are widely used, their potential to weaken dentin structure remains a concern. Polyhexanide-based formulations may offer a safer alternative.
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