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Background: Bell's palsy is an idiopathic facial palsy with an unknown cause, and 75% of patients heal spontaneously. However, the other 25% of patients continue experiencing mild or severe disabilities, resulting in a reduced quality of life. Currently, various treatment methods have been developed to treat this disease. However, there is controversy regarding their effectiveness, and new alternative treatments are needed.
Case Summary: The patient suffered from left-sided facial paralysis due to Bell's palsy for 7 years. The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment. After follow-up for 32 mo, the paralysis was cured, and there was no recurrence.
Conclusion: Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell's palsy who do not spontaneously recover.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198102 | PMC |
http://dx.doi.org/10.12998/wjcc.v11.i12.2817 | DOI Listing |
Int J Surg
September 2025
Department of Neurosurgery, Aviation General Hospital, Beijing, China.
Mil Med
September 2025
Soldier Centered Medical Home-CAB, Desmond Doss Health Clinic, Wahiawa, Hawaii, HI 96786, United States.
Guillain-Barré Syndrome (GBS) is an acute immune-mediated inflammatory demyelinating polyradiculopathy of the peripheral nerves often provoked by a preceding upper respiratory or gastrointestinal infection. Guillain-Barré Syndrome usually presents with symmetrical lower limb ascending weakness and decreased deep tendon reflexes. Here, we describe a case of an uncommon presentation of GBS presenting with upper extremity neuropathy and cranial nerve palsy in a 36-year-old Caucasian Army pilot.
View Article and Find Full Text PDFCranio
September 2025
Department of Neurosciences, University of Padua, Padua, Italy.
Background: Alternobaric facial palsy (AFP) is a rare peripheral facial nerve palsy resulting from transient neurapraxia when sudden ambient-pressure changes disrupt middle-ear equilibrium. Common precipitants include scuba diving, air travel, and altitude. AFP triggered by routine activities is exceedingly uncommon.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
September 2025
Department of Otorhinolaryngology, University of Health Sciences, Prof. Dr. Cemil Taşcıoğlu City Hospital, Istanbul, Turkey.
Purpose: To evaluate the prognostic significance of inflammatory markers, computed tomography (CT)-based facial nerve measurements, and clinical parameters in pediatric patients with Bell's palsy.
Methods: In this retrospective study, 136 patients aged 4-18 years diagnosed with Bell's palsy were evaluated. Clinical data included age, sex, affected side, initial House-Brackmann (HB) grade, recovery grades at one month and final follow-up, presence of pain, and treatment timing.
Facial Plast Surg Aesthet Med
August 2025
Section of Facial Plastic and Reconstructive Surgery, Head and Neck Department, Cleveland Clinic, Cleveland, Ohio, USA.
To evaluate objective and subjective outcomes in patients with ocular synkinesis before and 1 month after daily ophthalmic oxymetazoline, using standardized photographs, the Sunnybrook Facial Grading Scale, and patient-reported measures. Ophthalmic oxymetazoline, an alpha-adrenergic agonist Food and Drug Administration approved for acquired blepharoptosis, stimulates eyelid retractors but has not been studied for ocular synkinesis. Adult outpatients with ocular synkinesis self-administered 0.
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