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Auto-brewery syndrome (ABS) occurs when the gastrointestinal tract produces excessive endogenous ethanol. This article examines various aspects of ABS such as its epidemiology, underlying etiology, diagnostic difficulties, management strategies, and social implications. By synthesizing the existing medical literature, we hope to identify understanding gaps, pave the way for further research, and ultimately improve detection, treatment, and awareness. The databases we used are PubMed, PubMed Central, and Google Scholar. We carefully screened all published articles from inception till date and narrowed down 24 relevant articles. We at Richmond University Medical Center and Mount Sinai are one of the leading medical centers for diagnosing and treating this rare condition in the United States.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189828 | PMC |
http://dx.doi.org/10.7759/cureus.37678 | DOI Listing |
Am J Nurs
August 2025
Barbara Cordell is an adjunct professor of nursing at Panola College in Carthage, TX. She is president of Auto-Brewery Syndrome Information and Research (ABSIR), a nonprofit advocacy group for patients with auto-brewery syndrome (ABS), and has authored a book on ABS that is featured on the ABSIR web
Auto-brewery syndrome (ABS), also known as gut fermentation syndrome, is an underdiagnosed condition caused by an over-colonization of fermenting organisms in the gastrointestinal tract. These organisms-yeasts and, more recently recognized, bacteria-ferment carbohydrates into alcohol. The result is intoxication when not drinking, which may be accompanied by safety issues and even legal ramifications.
View Article and Find Full Text PDFMicrob Biotechnol
March 2025
Nova Institute for Health, Baltimore, Maryland, USA.
Advances in neuromicrobiology and related omics technologies have reinforced the idea that unseen microbes play critical roles in human cognition and behaviour. Included in this research is evidence indicating that gut microbes, through direct and indirect pathways, can influence aggression, anger, irritability and antisocial behaviour. Moreover, gut microbes can manufacture chemicals that are known to compromise cognition.
View Article and Find Full Text PDFJ Hepatol
April 2025
Microbiology Department, Ramón y Cajal Hospital and Institute Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Madrid, Spain; CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain; Faculty of Health Sciences, Alfonso X El Sabio University (UAX), Villanue
Orv Hetil
November 2024
1 Elméleti Biológiai Kutatócsoport Budapest Magyarország.
Auto-brewery or intestinal fermentation syndrome is a rare disorder in which the symptoms of alcohol intoxication of varying severity develop without alcohol consumption. The fermentation activity of the altered intestinal microbiome is responsible for endogenous alcohol production. The set of symptoms not only raises differential diagnostic questions, but also has serious legal implications due to the resulting alcohol intoxication.
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