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In 2011, (EME) was described as a human pathogen spread by the blacklegged tick, . Until very recently, its reported distribution was limited to the upper midwestern United States, mainly in Minnesota and Wisconsin. In this study, we report the detection of EME DNA in 4 of 16,146 human biting ticks submitted from Massachusetts to a passive tick surveillance program. Active tick surveillance yielded evidence of EME local transmission in the northeastern United States through detection of EME DNA in 2 of 461 host-seeking nymphs, and in 2 white-footed mice () of 491 rodent samples collected in the National Ecological Observatory Network (NEON) Harvard Forest site in Massachusetts.
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http://dx.doi.org/10.1089/vbz.2022.0098 | DOI Listing |
eNeuro
September 2025
Institute for Behavioral Medicine Research, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA
Chemotherapy can cause debilitating behavioral side effects (e.g., fatigue, depression, cognitive decline); however, having an intimate partner can buffer these effects.
View Article and Find Full Text PDFInfect Immun
September 2025
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
Ticks are obligate hematophagous parasites and pathogen vectors responsible for morbidity and mortality worldwide. is a vector for at least seven pathogens relevant to human and animal health, including the Lyme disease microbe, , and the causative agent of anaplasmosis, . Tick-host interactions affect the maintenance of tick-borne pathogens in a population.
View Article and Find Full Text PDFBrain Behav Immun Health
October 2025
Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA, USA.
The California mouse is a biparental monogamous rodent species used to study the neuroendocrine mechanisms underlying social stressors, but there is limited research investigating the neuroimmune response within the species to facilitate our understanding of stress and neuroinflammation interactions. The data herein provide an assessment of behavior, somatic metrics, and gene expression changes within the prefrontal cortex (PFC) and hippocampus (HPC) at 4- and 24-h following a single peripheral injection of the endotoxin lipopolysaccharide (LPS) in males and females. We observed effects of LPS on spleen weights and both males and females demonstrated sickness-like behaviors at 24 h as indicated by assessment of nest building quality.
View Article and Find Full Text PDFPopulations that colonize islands experience novel selective pressures, fluctuations in size, and changes to their connectivity. Owing to their unique geographic setting, islands can function as natural laboratories in which to examine the interactions between demographic history and natural selection replicated across isolated populations. We used whole genome sequences of wild-caught deer mice ( ) from two islands (Saturna and Pender) and one mainland location (Maple Ridge) in the Gulf Islands region of coastal British Columbia to investigate two primary determinants of genome-wide diversity: chromosomal inversions and non-equilibrium demographic history.
View Article and Find Full Text PDFPathogens
July 2025
Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center (UNMC), Omaha, NE 68198, USA.
Sin Nombre virus (SNV) is the main causative agent of hantavirus cardiopulmonary syndrome (HCPS) in North America. SNV is transmitted via environmental biological aerosols (bioaerosols) produced by infected deer mice (). It is similar to other viruses that have environmental transmission routes rather than a person-to-person transmission route, such as avian influenza (e.
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