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Study Objective: To evaluate the feasibility of laparoscopic rectosigmoid resection for bowel endometriosis (RSE), reporting surgical and short-term postoperative outcomes in a consecutive large series of patients.
Design: A retrospective cohort study.
Setting: Third-level national referral center for deep endometriosis (DE).
Patients: 3050 patients with symptomatic RSE requiring surgical treatment.
Interventions: Nerve-sparing laparoscopic resection for RSE perfomed by a multidisciplinary team. After collecting intraoperative surgical characteristics, postoperative complications were collected by evaluating the risk factors associated with their onset.
Measurements And Main Results: Clavien-Dindo IIIb postoperative complications were noted in 13.1% of patients, with anastomotic leakage and rectovaginal fistula accounting for 3.0% and 1.9%, respectively. Postoperative bladder impairment was observed in 13.9% of patients during hospital discharge but spontaneously decreased to 4.5% at the first evaluation after 30 days, alongside a statistically significant change towards global symptom improvement. Multivariate analyses were done to identify the risk factors for segmental bowel resection in terms of occurrence of postoperative major complications. Ultralow (≤5 cm from the anal verge), low rectal anastomosis (<8 cm, >5 cm), parametrectomy, vaginal resection, and previous surgeries seemed more related to anastomotic leakage, rectovaginal fistula, and bladder retention.
Conclusions: Laparoscopic rectosigmoid resection for RSE seems an effective and feasible procedure. The surgical complication rate is not negligible but could be reduced by implementing a multidisciplinary approach, an endless improvement in nerve-sparing techniques and surgical anatomy, as well as technological enhancements. Real future challenges will be to reduce the time for the first diagnosis of DE and the likelihood of surgical indications.
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http://dx.doi.org/10.1016/j.jmig.2023.04.005 | DOI Listing |
Lancet Gastroenterol Hepatol
October 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; Endoscopy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.
Background: Guidelines recommend leaving in situ rectosigmoid polyps diagnosed during colonoscopy that are 5 mm or smaller if the endoscopist optically predicts them to be non-neoplastic. However, no randomised controlled trial has been done to examine the efficacy and safety of this strategy.
Methods: This open-label, multicentre, non-inferiority, randomised controlled trial enrolled adults age 18 years or older undergoing colonoscopy for screening, surveillance, or clinical indications across four Italian centres.
Eur J Surg Oncol
August 2025
Department of Surgery, University Medical Center Groningen, University of Groningen, the Netherlands. Electronic address:
Background: The rate of incomplete resection in the surgical treatment of locally advanced primary rectal cancer and locally recurrent rectosigmoid cancer is high. The use of optical stereotactic navigation during surgery has the potential to reduce this risk. This study evaluates the feasibility of its implementation by assessing navigational accuracy and oncological outcomes.
View Article and Find Full Text PDFElectrolyte depletion syndrome (EDS), also known as McKittrick-Wheelock syndrome, is a rare but life-threatening condition caused by secretory diarrhea from colorectal villous tumors, often accompanied by severe electrolyte imbalances and renal dysfunction. Large, circumferential tumors have traditionally been managed with surgical resection, frequently requiring stoma formation. Recently, endoscopic submucosal dissection (ESD) has emerged as a minimally invasive alternative, although its feasibility for large rectal tumors remains limited.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Department of Radiology, Faculty of Medicine and Health Science, Sana'a University, Sana'a City, Yemen.
Introduction: Malignant peripheral nerve sheath tumors (MPNSTs) are rare and aggressive soft tissue sarcomas. Its occurrence in the gastrointestinal tract, particularly in the sigmoid colon, is exceptionally uncommon and poses significant diagnostic and therapeutic challenges.
Case Presentation: We report the case of a 46-year-old female who presented with a four-year history of intermittent rectal bleeding and lower abdominal pain.
Int J Surg Case Rep
August 2025
Hospital Universitari de Bellvitge, Hospitalet de Llobregat, Spain. Electronic address:
Introduction And Importance: Massive segmental bone defects constitute a complex therapeutic challenge. The most widely-accepted techniques to address such defects, i.e.
View Article and Find Full Text PDF