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Objective: To compare patient outcomes at the time of the return to activity (RTA) progression between those with a prior interim assessment and those without.
Design: Retrospective, Cohort Study.
Setting: Controlled Laboratory.
Participants: Patients following Anterior Cruciate Ligament Reconstruction (ACLR) were recruited through an ongoing RTA assessment program. Patients were stratified into two testing groups = "Single RTA test": only assessment between 6 and 9 months post-ACLR and "Repeat RTA test": prior assessment performed >2-months before their RTA assessment. Patients were matched based on time post-surgery, age, activity level, and graft type.
Main Outcome Measure: Self-reported knee function and isokinetic knee flexor and extensor strength/symmetry were compared between groups.
Results: 392 patients were identified. Once matched, 138 patients (21.1 ± 7.0 years, 7.3 ±0 .9 mo post-ACLR) were analyzed. Repeat RTA test patients demonstrated higher measures of self-reported knee function (P = .04) and greater knee flexion strength (P = .006) and symmetry (P = .05).
Conclusion: Patients with interim functional assessments reported greater self-reported knee function and higher hamstring strength at the time of RTA compared to patients that completed their only assessment within this time point. Early functional assessments may identify individualized deficits that can be addressed while patients are under supervision of rehabilitation specialists.
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http://dx.doi.org/10.1016/j.ptsp.2023.04.006 | DOI Listing |
J Trace Elem Med Biol
September 2025
Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, Kraków 31-343, Poland. Electronic address:
Vanadium (V) is a trace element in the environment; it is detected in soil, water, air, dust, and food products. V-containing compounds have shown therapeutic potential in the treatment of diabetes. However, studies on the effects of V on animal behavior remain limited and sporadic.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
National Institute of Public Health, University of Southern Denmark, Copenhagen K, Denmark.
Background: The high and increasing rate of poor mental health among young people is a matter of global concern. Experiencing poor mental health during this formative stage of life can adversely impact interpersonal relationships, academic and professional performance, and future health and well-being if not addressed early. However, only a few of those in need seek help.
View Article and Find Full Text PDFNeuro Endocrinol Lett
September 2025
Faculty of Science, Jan Evangelista Purkyně University, Ústí nad Labem, Czech Republic.
Objective: In addition to hypogonadism, other endocrine disorders-particularly hyperprolactinemia-can significantly influence erectile dysfunction (ED) in men. The aim of our study was to evaluate the effect of normalizing prolactin (PRL) levels on erectile function in men diagnosed with ED and hyperprolactinemia. The primary outcome was improvement in IIEF-5.
View Article and Find Full Text PDFNeuro Endocrinol Lett
September 2025
Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey.
Objective: It is important to raise awareness of the nutritional problems that can be overlooked during the follow-up visits with children who suffer from neuromuscular diseases, as these dietary differences may lead to additional neurological and systemic problems and impair the quality of life of the patient. The aim of this study was to evaluate the nutritional status of children with neuromuscular disorders and to prevent possible complications by recognizing possible nutritional problems in advance.
Methods: Patients who applied to the outpatient clinic at Cukurova University, Faculty of Medicine, Department of Pediatric Neurology beginning in April 2022 with a neuromuscular disorder diagnosis were followed up with and were included in the study.
Evol Comput
September 2025
Computer Science Department, Tel-Hai College, and The Galilee Research Institute - Migal, Upper Galilee, Israel
Mixed-integer (MI) quadratic models subject to quadratic constraints, known as All- Quadratic MI Programs, constitute a challenging class of NP-complete optimization problems. The particular scenario of unbounded integers defines a subclass that holds the distinction of being even undecidable. This complexity suggests a possible soft-spot for Mathematical Programming (MP) techniques, which otherwise constitute a good choice to treat MI problems.
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