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Psychopathy comprises antagonistic personality traits and antisocial behaviors that are associated with critical outcomes for the individual and society (e.g., violent behavior). Since its inception, impulsivity has been theorized as a core feature of psychopathy. Research supports this assertion, yet psychopathy and impulsivity are both multifaceted constructs. As such, the associations commonly observed between psychopathy and impulsivity may obscure more nuanced profiles of impulsivity that are only observable at the facet-level. To address this gap in the literature, we collected data from a community sample using a clinical psychopathy interview along with dispositional and neurobehavioral measures of impulsivity. We regressed each of the four facets of psychopathy onto eight impulsivity variables. We followed these analyses with bootstrapped dominance analyses in order to determine which of the impulsivity variables shared the most variance with each psychopathy facet. Our analyses revealed that positive urgency was the most important aspect of impulsivity to all four facets of psychopathy. We further identified distinct profiles of impulsivity linked to each psychopathy facet-the interpersonal facet was typified by sensation seeking and temporal impulsivity. The affective and lifestyle facets were both typified by general trait impulsivity and affective impulsivity. The antisocial facet was typified by affective impulsivity and sensation seeking. Such distinct profiles of impulsivity suggest that specific behaviors linked with each facet (e.g., manipulativeness and the interpersonal facet) may be explained in part by the distinct forms of impulsivity aligned with them.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104332 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0283866 | PLOS |
J Am Acad Audiol
September 2025
Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder caused by tumor-mediated antibodies targeting the cerebellum, often leading to irreversible cerebellar damage. The most common antibody implicated in PCD is anti-Purkinje cell cytoplasmic antibody type-1, associated with malignancies such as breast, gynecological, and lung cancers. Symptoms often include dizziness, imbalance, progressive ataxia, and other cerebellar signs/symptoms, but early presentations may mimic acute vestibular syndrome, thus complicating diagnosis.
View Article and Find Full Text PDFIntroduction: The present study examined whether college students could be categorized into distinct subgroups that differed in their distracted driving and walking frequencies.
Method: A sample of 277 college students participated in this study. They completed an online survey measuring their frequencies of distracted driving and walking, trait impulsivity (relatively stable characteristics of individuals to act spontaneously without considering the potential consequences), and behavioral impulsivity (process-oriented construct reflecting impulsive decision-making).
J Am Coll Cardiol
September 2025
Institute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences and Public Health, University of Brescia, Brescia, Italy. Electronic address:
Secondary mitral regurgitation (SMR) is common in patients with heart failure (HF). Although randomized clinical trials have been focused on the treatment of severe SMR, the prognostic role and potential for treatment of moderate SMR cannot be overlooked. The randomized RESHAPE-HF2 trial included patients with moderate and severe SMR with consistent findings in both groups, raising the hypothesis that transcatheter correction of moderate SMR could have beneficial effects, although this needs further investigation.
View Article and Find Full Text PDFJACC Cardiovasc Interv
September 2025
The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Previous trials have demonstrated increased 5-year risks for adverse clinical events after coronary artery implantation of poly-l-lactic acid-based bioresorbable scaffolds (BRS) compared with cobalt chromium (CoCr) everolimus-eluting stents (EES).
Objectives: The aim of this study was to evaluate the 5-year clinical outcomes of the novel sirolimus-eluting NeoVas BRS compared with CoCr EES.
Methods: A total of 560 patients with single de novo native coronary artery lesions with reference vessel diameter 2.
Brain Res Bull
September 2025
Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for the Developing Mind, Children's Hospital Los Angeles, Los Angeles, CA.
We propose a Biophysically Restrained Analog Integrated Neural Network (BRAINN), an analog electrical network that models the dynamics of brain function. The network interconnects analog electrical circuits that simulate two tightly coupled brain processes: (1) propagation of an action potential, and (2) regional cerebral blood flow in response to the metabolic demands of signal propagation. These two processes are modeled by two branches of an electrical circuit comprising a resistor, a capacitor, and an inductor.
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