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Background: The Jagiellonian Positron Emission Tomograph is the 3-layer prototype of the first scanner based on plastic scintillators, consisting of 192 half-metre-long strips with readouts at both ends. Compared to crystal-based detectors, plastic scintillators are several times cheaper and could be considered as a more economical alternative to crystal scintillators in future PETs. JPET is also a first multi-photon PET prototype. For the development of multi-photon detection, with photon characterized by the continuous energy spectrum, it is important to estimate the efficiency of J-PET as a function of energy deposition. The aim of this work is to determine the registration efficiency of the J-PET tomograph as a function of energy deposition by incident photons and the intrinsic efficiency of the J-PET scanner in detecting photons of different incident energies. In this study, 3-hit events are investigated, where 2-hits are caused by 511 keV photons emitted in [Formula: see text] annihilations, while the third hit is caused by one of the scattered photons. The scattered photon is used to accurately measure the scattering angle and thus the energy deposition. Two hits by a primary and a scattered photon are sufficient to calculate the scattering angle of a photon, while the third hit ensures the precise labeling of the 511 keV photons.
Results: By comparing experimental and simulated energy distribution spectra, the registration efficiency of the J-PET scanner was determined in the energy deposition range of 70-270 keV, where it varies between 20 and 100[Formula: see text]. In addition, the intrinsic efficiency of the J-PET was also determined as a function of the energy of the incident photons.
Conclusion: A method for determining registration efficiency as a function of energy deposition and intrinsic efficiency as a function of incident photon energy of the J-PET scanner was demonstrated. This study is crucial for evaluating the performance of the scanner based on plastic scintillators and its applications as a standard and multi-photon PET systems. The method may be also used in the calibration of Compton-cameras developed for the ion-beam therapy monitoring and simultaneous multi-radionuclide imaging in nuclear medicine.
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http://dx.doi.org/10.1186/s40658-023-00546-7 | DOI Listing |
Cereb Cortex
March 2025
Neuropsychiatry, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
This study investigates the relationship between resting-state functional magnetic resonance imaging (rs-fMRI) topological properties and synaptic vesicle glycoprotein 2A (SV2A) positron emission tomography (PET) synaptic density (SD) in late-life depression (LLD). 18 LLD patients and 33 healthy controls underwent rs-fMRI, 3D T1-weighted MRI, and 11C-UCB-J PET scans to assess SD. The rs-fMRI data were utilized to construct weighted networks for calculating four global topological metrics, including clustering coefficient, characteristic path length, global efficiency, and small-worldness, and six nodal metrics, including nodal clustering coefficient, nodal characteristic path length, nodal degree, nodal strength, local efficiency, and betweenness centrality.
View Article and Find Full Text PDFEJNMMI Phys
October 2023
Department of Experimental Particle Physics and Applications, Faculty of Physics, Astronomy, and Applied Computer Science, Jagiellonian University, Kraków, Poland.
Background: Alongside the benefits of Total-Body imaging modalities, such as higher sensitivity, single-bed position, low dose imaging, etc., their final construction cost prevents worldwide utilization. The main aim of this study is to present a simulation-based comparison of the sensitivities of existing and currently developed tomographs to introduce a cost-efficient solution for constructing a Total-Body PET scanner based on plastic scintillators.
View Article and Find Full Text PDFEJNMMI Phys
April 2023
Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, prof. Stanisława Łojasiewicza 11, 30-348, Cracow, Poland.
Background: The Jagiellonian Positron Emission Tomograph is the 3-layer prototype of the first scanner based on plastic scintillators, consisting of 192 half-metre-long strips with readouts at both ends. Compared to crystal-based detectors, plastic scintillators are several times cheaper and could be considered as a more economical alternative to crystal scintillators in future PETs. JPET is also a first multi-photon PET prototype.
View Article and Find Full Text PDFJ Pet Explor Prod Technol
January 2023
Faculty of Petroleum and Natural Gas Engineering, Sahand University of Technology, Tabriz, 51335-1996 Iran.
Applications of nanotechnology in several fields of petroleum industry, e.g., refinery, drilling and enhanced oil recovery (EOR), have attracted a lot of attention, recently.
View Article and Find Full Text PDFJ Pet Explor Prod Technol
December 2021
Department of Mathematics, Faculty of Science, Zagazig University, Zagazig, 44519 Egypt.
Oil production forecasting is an important task to manage petroleum reservoirs operations. In this study, a developed time series forecasting model is proposed for oil production using a new improved version of the adaptive neuro-fuzzy inference system (ANFIS). This model is improved by using an optimization algorithm, the slime mould algorithm (SMA).
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