98%
921
2 minutes
20
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis which causes potentially debilitating pain and loss of mobility. Biologics represent a highly effective treatment option in AS. Nonetheless, the choice of biologics often involves complex decision-making. A web-based medical communication aid (MCA) was designed to support information exchange and shared decision-making process between physicians and biologics naïve AS patients. This study aimed to assess the usability of the MCA prototype and the understandability of the MCA contents among rheumatologists and AS patients in South Korea. This was a cross-sectional study using a mixed-methods approach. Treating rheumatologists from major hospitals and their AS patients were recruited in this study. Participants navigated through the MCA and provided feedbacks, guided by interviewers using the think-aloud (TA) method. Participants were then asked to complete a set of surveys. The qualitative and quantitative data were analyzed to determine the usability of the MCA prototype and the understandability of the MCA contents. The MCA prototype received above average rating for usability and high rating for the understandability of its contents. Additionally, participants rated that the quality of information presented in the MCA as high. Analysis of the qualitative data highlighted three key aspects of the MCA; the usefulness of the MCA, the need to present concise and relevant content; and the importance of an intuitively designed tool. Overall, participants found the MCA to be potentially valuable in supporting the current unmet needs in clinical care and had expressed a willingness to use the MCA. The MCA had great potential in supporting shared decision-making by improving patients' knowledge on disease and treatment options, as well as clarifying patients' personal preferences and values in the management of AS.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082296 | PMC |
http://dx.doi.org/10.1097/MD.0000000000033430 | DOI Listing |
This paper presents a novel multiscale signal processing framework for power quality disturbance (PQD) and cyber intrusion detection in smart grids, combining Non-Subsampled Contourlet Transform (NSCT), Split Augmented Lagrangian Shrinkage Algorithm (SALSA), and Morphological Component Analysis (MCA). A key innovation lies in an adaptive weighting mechanism within NSCT's directional sub bands, enabling dynamic energy redistribution and enhanced representation of both low-frequency anomalies (e.g.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Computer Science and Artificial Intelligence, College of Computing and Information Technology, University of Bisha, Bisha, Saudi Arabia.
The Internet of Things (IoT) includes vehicles, homes, and integrated sensors and many interconnected physical devices that gather and share data to interact with their environment. Data moving across multiple levels is vulnerable to various security threats, including leaks and unauthorized access. IoT faces significant challenges in balancing strict security with optimal performance metrics such as energy efficiency, throughput, and memory.
View Article and Find Full Text PDFTurk Neurosurg
October 2024
Department of Neurosurgery.
Intracranial aneurysms are rare in the pediatric population, while fusiform middle cerebral artery (MCA) aneurysms are more common. Although surgical clipping is the generally preferred treatment strategy for aneurysms, occasional recurrence may still occur after successful clipping. As expertise in the use of flow diverters in adults has developed, they have also been applied in the management of aneurysms in children.
View Article and Find Full Text PDFThromb J
September 2025
C-Care International Hospital Kampala, Plot 4686 Barnabas Road, Kampala, Uganda.
Background: Majority of people with "kissing carotids", an anatomical variation of the cervical carotid arteries showing tortuosity, kinking or coiling and coming in proximity at the midline are asymptomatic. Less than 1% of the general population have Protein S Deficiency. This report discusses a rare case of a young female with co-existent Protein S deficiency and kissing carotids, who presented with sequential thrombosis in both arterial and venous cerebral circulation systems and further discusses potential mechanisms of arterial thrombosis in Protein S deficiency and medical options for secondary stroke prophylaxis in this context.
View Article and Find Full Text PDFJ Neurotrauma
September 2025
The Max Harry Weil Institute for Critical Care Research and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
Cerebrovascular autoregulation (CA) is a protective mechanism against brain injury. We present an ultrasound-based volumetric blood flow indices to monitor CA. Swine were instrumented under general anesthesia to monitor mean arterial blood pressure (MAP), intracranial pressure (ICP), and blood flow in the internal carotid artery (ICA) and femoral artery (FA) and flow velocity and volumetric flow in the middle cerebral artery (MCA) using transcranial Doppler.
View Article and Find Full Text PDF