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The synergistic effect of Cu-MOF nanoparticles and immunomodulatory agent on SARS-CoV-2 inhibition. | LitMetric

The synergistic effect of Cu-MOF nanoparticles and immunomodulatory agent on SARS-CoV-2 inhibition.

Chem Commun (Camb)

Adam Mickiewicz University, Faculty of Chemistry, Department of Chemical Technology, Uniwersytetu Poznańskiego 8, Poznań 61-614, Poland.

Published: April 2023


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Article Abstract

In this work, HKUST-1 and Cu-BDC nanoparticles were used as delivery systems for the early anti-COVID-19 drug, hydroxychloroquine. The antiviral MOF/drug combinations significantly reduced the infectivity of SARS-CoV-2, which can be attributed to the nanometric size of the carriers, the presence of copper in the MOF nodes, and the semi-controlled release of the drug.

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Source
http://dx.doi.org/10.1039/d3cc00894kDOI Listing

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