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(1) Background: weight-management interventions vary in their delivery features and intervention strategies. We aimed to establish a protocol to identify these intervention components. (2) Methods: a framework was developed through literature searches and stakeholder consultation. Six studies were independently coded by two reviewers. Consensus included recording conflict resolutions and framework changes. (3) Results: more conflicts occurred for intervention strategies compared to delivery features; both required the updating of definitions. The average coding times were 78 min (SD: 48) for delivery features and 54 min (SD: 29) for intervention strategies. (4) Conclusions: this study developed a detailed framework and highlights the complexities in objectively mapping weight-management trials.
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http://dx.doi.org/10.3390/nu15061414 | DOI Listing |
Adv Sci (Weinh)
September 2025
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.
Traumatic Brain Injury (TBI) is a common and debilitating injury, causing long-lasting neurological deficits. Current therapeies for recovery remain inadequate, undersing the urgent need for innovative interventions. In this study, a novel therapeutic approach is introduced that delivers extracellular vesicles (EVs) derived from human-induced pluripotent stem cell-derived neural progenitor cells (hiPSC-NPCs) with a gelatin-based injectable bioorthogonal hydrogel (BIOGEL).
View Article and Find Full Text PDFGlob J Qual Saf Healthc
August 2025
Metropolitan School of Business and Management, London, UK.
Introduction: Telemedicine, also known as e-health, utilizes computer technology to deliver clinical healthcare remotely. Since its inception in the 1960s, telemedicine has evolved significantly, offering several advantages to both patients and healthcare providers, including remote care and monitoring. This study contributes to existing literature by exploring the effectiveness of telemedicine and patient satisfaction in managing health conditions in Canada, with a focus on service delivery, accessibility, efficiency, doctor-patient relationships, and network interconnectivity.
View Article and Find Full Text PDFFront Microbiol
August 2025
State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Autism spectrum disorders (ASD), a group of neurodevelopmental disorders characterized by the core symptoms of impaired social communication and stereotyped behaviors, is strongly associated with dysregulated microbiota-gut-brain axis. Emerging evidence suggests that , which showed reduced abundance in ASD cohorts, holds therapeutic potential, though its interaction with host remain unexplored. Here, we investigated the efficacy and molecular basis of 4P-15 (4P-15) in BTBR /J (BTBR) mice, an idiopathic ASD mouse model.
View Article and Find Full Text PDFAm J Prev Cardiol
September 2025
Department of Cardiology, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.
Background: Data on outcomes associated with various modes of delivery in pregnant patients with heart failure (HF) or pulmonary hypertension (pHTN) are limited.
Objective: We aim to investigate the association between mode of delivery on maternal and fetal outcomes in pregnant patients with HF or pHTN by conducting a multicenter, large scale and nationwide retrospective cohort study.
Methods: This retrospective population-based cohort study used the Nationwide Readmission Database to identify all hospitalized pregnant patients who were primarily admitted for vaginal or cesarean delivery from 2011 to 2019.
Cureus
August 2025
Department of Anaesthesiology, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, ISR.
Pregnancy in women with Ehlers-Danlos syndrome (EDS) carries elevated risks, including prematurity, hemorrhage, and maternal morbidity, posing significant anesthetic challenges. We present the case of a 36-year-old woman with classical EDS (cEDS) and multiple comorbidities, including postural orthostatic tachycardia syndrome, bronchial asthma, congenital adrenal hypoplasia, and chronic venous thrombosis, who underwent an elective cesarean section. A multidisciplinary team developed a comprehensive perioperative plan featuring ultrasound-guided spinal anesthesia, extended post-anesthesia observation, and coordinated recommendations from cardiology, hematology, endocrinology, pulmonology, and other specialties.
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