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Medication adherence, especially among children and adolescents with psychiatric disorders, is often seen as a major treatment challenge. The purpose of this study is to systematically review studies addressing specific aspects of parental factors that are positively or negatively associated with medication adherence among children and adolescents with psychiatric disorders. A systematic literature search of English language publications, from inception through December 2021, was conducted from PubMed, Scopus, and MEDLINE databases. This review has complied with Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines. A total of 23 studies (77,188 participants) met inclusion criteria. Nonadherence rates ranged between 8% to 69%. Parents' socioeconomic background, family living status and functioning, parents' perception and attitude towards the importance of medication taking in treating psychiatric disorders, and parents' mental health status are significant parental characteristics associated with medication adherence in children and adolescents with psychiatric disorders. In conclusion, by identifying specific parental characteristics related to the medication adherence of children and adolescents with psychiatric disorders, targeted interventions on parents could be developed to guide parents in improving their child's medication adherence.
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http://dx.doi.org/10.3390/healthcare11040501 | DOI Listing |
Eur J Clin Pharmacol
September 2025
Department of Clinical Pharmacy and Pharmacology, University of Groningen, and University Medical Center Groningen, Groningen, The Netherlands.
Purpose: Non-adherence to inhaled medication poses a significant clinical and economic burden on patients with respiratory diseases. This narrative review provides an overview of key aspects of hair analysis, in general and specific for inhaled medications, and explores the potential of hair analysis as a novel tool to monitor adherence to inhaled medications.
Methods: PubMed searches were conducted to explore four aspects: (1) mechanisms of (inhaled) drug's systemic absorption and deposition in hair; (2) quantification of drugs in hair; (3) factors impacting (inhaled) drug hair concentrations; and (4) clinical studies assessing inhaled medication adherence through hair analysis.
J Korean Med Sci
September 2025
Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Background: Readily available treatments for Alzheimer's disease and related dementia (ADRD) include acetylcholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists. Non-adherence and early discontinuation of anti-dementia medications are prevalent issues. We aimed to investigate factors associated with suboptimal usage of anti-dementia medications in ADRD.
View Article and Find Full Text PDFCureus
August 2025
Community Medicine Management, Shimane University, Izumo, JPN.
This systematic review synthesized findings from 17 studies conducted between 2000 and 2024, focusing on the definitions, interventions, and outcomes associated with community nursing. The studies originated from diverse countries, including Singapore, Australia, Italy, Portugal, and the United States, and employed various designs such as quasi-experimental trials, pre-post evaluations, and descriptive studies. Sample sizes ranged from 23 to over 1,600 participants, with most targeting older adults or individuals with chronic conditions.
View Article and Find Full Text PDFS Afr Fam Pract (2004)
August 2025
Department of Family Medicine, Faculty of Health Sciences, University of Limpopo, Mankweng.
Background: Non-adherence to treatment remains a major contributing factor to uncontrolled hypertension and its complications. In South Africa, an estimated 50% of adults are living with hypertension and between 41.9% and 45.
View Article and Find Full Text PDFJ Med Syst
September 2025
Department of Nursing, ESEP - Porto Higher School of Nursing, Rua Dr. António Bernardino de Almeida, nº 830, Porto, 4200-072, Portugal.
To address the challenges of self-care in oncology, gamification emerges as an innovative strategy to enhance health literacy and self-care among individuals with oncological disease. This study aims to explore and map how gamification can promote health literacy for self-care of oncological diseases. A scoping review was conducted following the Joanna Briggs Institute guidelines and the PRISMA-ScR Checklist developed for scoping reviews.
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