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Paranormal believers' thinking is frequently biased by intuitive beliefs. Lack of inhibition of these tempting beliefs is considered a key element in paranormal believers' thinking. However, the brain activity related to inhibitory control in paranormal believers is poorly understood. We examined EEG activities at resting state in alpha, beta, and gamma bands with inhibitory control in paranormal believers and skeptics. The present study shows that paranormal belief is related to the reduced power of the alpha, beta, and gamma frequency bands, and reduced inhibitory control. This study may contribute to understanding the differences between believers and skeptics in brain activity related to inhibitory control in paranormal believers.
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http://dx.doi.org/10.1038/s41598-023-30457-7 | DOI Listing |
Neotrop Entomol
September 2025
Dept of Zoology, Government College Univ Lahore, Lahore, Pakistan.
The control of dengue vector mosquitoes by utilizing plant-based eco-friendly larvicides is pivotal in suppressing the spread of dengue with minimum environmental toxicity. This study aimed to evaluate the larvicidal activity of nanoliposomes containing p-cresol and Myristica fragrans Houtt. essential oil (EO) against Aedes aegypti L.
View Article and Find Full Text PDFBioorg Med Chem Lett
September 2025
Department of Chemical Engineering, Analysis and Test Center, Shenyang University of Chemical Technology, Shenyang 110142, China. Electronic address:
Asiatic acid (AA) was used as the lead compound and 22 inhibitors of specificity protein 1 (Sp1) were designed and synthesized with modification at A ring and C-28 position of AA, whose structures were confirmed by HRMS, H NMR and C NMR. The growth inhibitory effects of Asiatic acid derivatives on human breast cancer cells (MCF-7) and cervical cancer cells (Hela) were determined by tetramethyl azole salt (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, MTT) colorimetric assay. The results showed that all of these compounds inhibited the proliferation of HeLa and MCF-7 cells, and all the derivatives showed stronger tumor cytotoxicity than AA, among which compounds I, II, and III were comparable to the positive control drug cisplatin.
View Article and Find Full Text PDFOsteoarthritis Cartilage
September 2025
Department of Clinical & Experimental Medicine, Brighton & Sussex Medical School, Brighton BN1 9PX, UK. Electronic address:
Objective: Therapeutic potential of selective aggrecanase inhibition in osteoarthritis (OA) was previously demonstrated using a variant of endogenous tissue inhibitor of metalloproteinase-3 (TIMP-3); however, this relied on transgenic mice overexpressing TIMP-3. Here, we develop a translational approach for harnessing the aggrecanase-selective inhibitory activity of TIMP-3 using the latency associated peptide (LAP) technology.
Methods: We successfully produced and purified recombinant LAP-TIMP-3 fusion proteins and determined the pharmacokinetics of these proteins in vivo following systemic injection.
PLoS One
September 2025
Shenzhen University Institute for Advanced Study, Shenzhen, Guangdong, China.
Trichophyton rubrum, a dermatophyte, demonstrates a notable ability to form mature biofilms on skin and associated surfaces, strengthening its resistance to antifungal agents. This characteristic poses intricate challenges in dermatological research and therapeutic strategies, underscoring the need for innovative approaches to effectively manage fungal infections. This work assessed the impact of the anti-biofilm enzymes, i.
View Article and Find Full Text PDFLasers Med Sci
September 2025
Laser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Microbial contamination of absorbable collagen membranes used in guided bone regeneration (GBR) may compromise healing outcomes. This study aimed to investigate whether the minimum inhibitory concentration (MIC) of hydrogen peroxide (HO) can improve the antibacterial effect of indocyanine green (ICG)-mediated antimicrobial photodynamic therapy (PDT) on absorbable collagen membranes while reducing the need for high HO concentrations. A laboratory-based model was developed using Streptococcus sanguinis and Staphylococcus aureus.
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