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Article Abstract
Purpose: Benign phyllodes tumors (BPT) are rare breast neoplasms with clinical behavior that poses low recurrence risk. Guidelines regarding appropriate margins recommend surgical excision to negative margins, sometimes requiring re-excision surgery. Contemporary experience suggests that re-excision in the face of positive margins may not be needed.
Methods: This is a retrospective review of a single-institution experience with BPT from 2010 to 2019 with 102 patients. Demographics, outcomes and follow-up were analyzed.
Results: The median age was 37 years. 95% had a pre-operative biopsy and only 6% were confirmed BPT before surgery.56% had positive margins and were more likely to be younger and have a pre-operative diagnosis of fibroadenoma. The median follow-up was 33 months. Between the positive and negative margin groups, recurrence rates were not significantly different (p = 0.87).
Conclusion: Positive margins on excision of BPT poses a low recurrence risk and re-excision surgery is not necessary.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11225600 | PMC |
| http://dx.doi.org/10.1007/s10549-023-06885-4 | DOI Listing |
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