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Fiberoptic intubation for a difficult airway requires significant experience. Traditionally only normal airways were available for high fidelity bronchoscopy simulators. It is not clear if training on difficult airways offers an advantage over training on normal airways. This study investigates the added value of difficult airway scenarios during virtual reality fiberoptic intubation training. A prospective multicentric randomized study was conducted 2019 to 2020, among 86 inexperienced anesthesia residents, fellows and staff. Two groups were compared: Group N (control, n = 43) first trained on a normal airway and Group D (n = 43) first trained on a normal, followed by three difficult airways. All were then tested by comparing their ORSIM® scores on 5 scenarios (1 normal and 4 difficult airways). The final evaluation ORSIM® score for the normal airway testing scenario was significantly higher for group N than group D: median score 76% (IQR 56.5-90) versus 58% (IQR 51.5-69, p = 0.0039), but there was no difference in ORSIM® scores for the difficult intubation testing scenarios. A single exposure to each of 3 different difficult airway scenarios did not lead to better fiberoptic intubation skills on previously unseen difficult airways, when compared to multiple exposures to a normal airway scenario. This finding may be due to the learning curve of approximately 5-10 exposures to a specific airway scenario required to reach proficiency.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882961 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0281016 | PLOS |
STAR Protoc
September 2025
UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital, Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; UCLA Environmental and Molecular Toxicology Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA
Exposure systems to study the effects of environmental exposures can be costly to purchase and difficult to use. Here, we present an accessible and cost-effective approach to building an exposure chamber in the lab. We describe steps for constructing the exposure system and writing the code to run it and simple instructions for experiments using the system.
View Article and Find Full Text PDFBackground: Actinomyces graevenitzii is a relatively uncommon Actinomyces species, which is an oral species and predominantly recovered from respiratory locations [1,2]. It is a gram-positive anaerobic bacteria or microaerobic filamentation bacteria, which can induce pyogenic and granulomatous inflammation characterized by swelling and concomitant pus, sinus formation, and the formation of yellow sulfur granules. All tissues and organs can be infected; the most common type involves the neck and face (55%), followed by the abdominal and pelvic cavities (20%).
View Article and Find Full Text PDFTher Adv Respir Dis
September 2025
Department of Respiratory Medicine, Shangyu People's Hospital of Shaoxing, Zhejiang, China.
Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition associated with increased morbidity and mortality, particularly during respiratory infections such as influenza. The interaction between COPD and influenza is multifaceted, involving compromised immune responses, chronic inflammation, and impaired lung function. Influenza infection can exacerbate COPD, leading to acute exacerbations, hospitalizations, and higher mortality.
View Article and Find Full Text PDFCureus
August 2025
Anesthesiology, Asahi General Hospital, Asahi, JPN.
Awake tracheal intubation (ATI) is a crucial technique for difficult airway management, particularly in patients with obesity, restricted neck movement, or upper airway abnormalities. Despite its efficacy, ATI is often avoided because of the technical challenges and stress it imposes on patients and anesthesiologists. We describe a new method, termed "intubation maintaining spontaneous breathing with three nerve blocks technique" (3N technique), which leverages nerve blocks to suppress reflexes, preserve spontaneous breathing, and facilitate smooth intubation.
View Article and Find Full Text PDFCurr Opin Pulm Med
September 2025
Division of Infectious Diseases, Department of Medicine.
Purpose Of Review: Cystic fibrosis (CF) and non-CF bronchiectasis can predispose patients to airway infections that are difficult to treat. The purpose of this review is to discuss recently developed anti-infectives which show promise in treating these infections.
Recent Findings: The microbiology underlying respiratory tract infections in persons with CF (pwCF) and non-CF bronchiectasis is complex.