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Article Abstract
Introduction: The efficacy of high-flow oxygen versus conventional oxygen therapy for asthma control remains controversial.
Aim: This meta-analysis aims to explore the influence of high-flow oxygen versus conventional oxygen therapy on asthma control.
Material And Methods: We have searched PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases, and included randomized controlled trials (RCTs) assessing the efficacy of high-flow oxygen versus conventional oxygen therapy for asthma control.
Results: Four RCTs are included in this meta-analysis. Overall, compared with conventional oxygen therapy for asthma, high-flow oxygen is associated with a significantly lower dyspnoea score (standard mean difference (SMD) = -0.63; 95% confidence interval (CI): -1.08 to -0.17; = 0.008), but reveals no remarkable influence on PaCO (SMD = 0.28; 95% CI: -0.22 to 0.77; = 0.28), PaO (SMD = 0.44; 95% CI: -1.34 to 2.22; = 0.63), intubation rate (OR = 1.09; 95% CI: 0.15 to 8.21; = 0.93) or hospital length of stay (SMD = -0.07; 95% CI: -0.41 to 0.27; = 0.67).
Conclusions: High-flow oxygen may benefit to reduce/may be more beneficial in reducing the dyspnoea score than conventional oxygen therapy for asthma, but shows no improvement in PaCO, PaO, intubation or hospital length of stay.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837591 | PMC |
| http://dx.doi.org/10.5114/ada.2022.119074 | DOI Listing |
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