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The massa intermedia (MI) or interthalamic adhesion (ITA) is a band of tissue connecting the medial surfaces of the thalami and is present in the majority of healthy individuals. Its enlargement as well as its absence have been associated with some pathological states.We describe the first case report of a 3-year-old child presenting with obstructive hydrocephalus in the context of an enlarged massa intermedia. The patient's symptoms abated following an endoscopic third ventriculostomy.
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http://dx.doi.org/10.1080/02688697.2022.2159924 | DOI Listing |
Ann Anat
September 2025
Department of Normal and Clinical Anatomy, University of Rzeszow, Medical College, Poland. Electronic address:
The interthalamic adhesion, or massa intermedia, is a midline bridge of neural tissue connecting the thalami across the third ventricle and usually containing the nucleus reuniens. It is important radiologically and neurosurgically: accessing the third ventricle or structures through the third ventricle, endoscopic surgery at third ventricle. We aim to consolidate current knowledge on the interthalamic adhesion, focusing on its morphology, nomenclature, development, histology, connections and anatomical variations to clarify longstanding inconsistencies.
View Article and Find Full Text PDFChilds Nerv Syst
June 2025
Radiology Department, Mansoura University Hospitals, Mansoura University Faculty of Medicine, Mansoura, Egypt.
Purpose: Post-myelomeningocele (MMC) repair hydrocephalus is associated with intraventricular anomalies that influence the outcomes of endoscopic third ventriculostomy (ETV) and choroid plexus cauterization (CPC). This study aimed to evaluate the sensitivity of FIESTA-C/CISS MRI in detecting anatomical variants with potential surgical implications during ETV and CPC.
Methods: A prospective study was conducted over a 2-year period on 23 patients with hydrocephalus following MMC repair.
Childs Nerv Syst
June 2025
Department of Neurosurgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Purpose: How myelomeningocele (MMC) level affects early brain development and hydrocephalus rates after prenatal repair is not well understood. This study aimed to determine differences in brain development and need for cerebrospinal (CSF) diversion in MMC patients according to lesion level and timing of repair.
Methods: We retrospectively identified patients from Barnes-Jewish/St.
The massa intermedia (MI) is a midline structure connecting the left and right thalamus that typically develops during the 2 trimester of pregnancy. Missing and smaller MI has been linked to neurodevelopmental disorders, including schizophrenia (SZ), and subtle deficits in cognition. However, findings are inconsistent and the association between MI and other anatomical variants linked to atypical brain development in SZ, including incomplete hippocampal inversion (IHI), is unclear.
View Article and Find Full Text PDFJ Neurosurg
April 2025
Departments of1Neurosurgery and.