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Purpose: The purpose of this study was to explore the impact of diabetic foot ulcer (DFU) on individuals' lives and daily routines.
Design: Qualitative design informed by social constructivism and symbolic interactionism frameworks.
Subjects And Setting: The sample comprised 30 individuals attending a wound care clinic in Southeast Ontario, Canada. Most participants (n = 17) were between the ages of 65 and 92 years, were male (n = 20), married (n = 21), living with their family (n = 23), and had completed high school (n = 26).
Methods: One-to-one semistructured interviews were conducted by the first author until saturation of each emerging theme was achieved. Interviews were audio-recorded and lasted from 45 to 90 minutes. Data collection and analysis occurred simultaneously and included intensive semistructured interviews, field notes, and researcher's journal.
Results: Participants with DFUs were found to perceive a "sense of life change," impacting their lives across physical, psychological, and social spheres. They reported 4 key themes indicating that DFUs were (1) limiting their outings; (2) restricting leisure activities; (3) impacting personal and social life; and (4) contributing to emotional fluctuations.
Conclusion: Sense of life changes resulting from DFUs were associated with participant reporting loss of freedom and enjoyment. These findings underscore the need for holistic support for patients with DFUs that simultaneously address physical, psychological, and social needs and areas of impact.
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http://dx.doi.org/10.1097/WON.0000000000000941 | DOI Listing |
Obes Surg
September 2025
Department of General and Visceral Surgery, University Hospital Brandenburg an der Havel, Brandenburg an der Havel, Germany.
Background: Perioperative antibiotic prophylaxis (PAP) prior to laparoscopic gastric bypass surgery is still under debate due to a lack of high evidence. Thus, the study at hand aimed to find out whether this medication lowers the rate of postoperative complications or not.
Methods: In 2020, a retrospective analysis took place at Helios Hospital Berlin Buch, Germany.
Eur J Clin Pharmacol
September 2025
Department of Forensic Pathology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, China.
Background And Objective: While current clinical guidelines generally advocate for beta-blocker therapy following acute myocardial infarction (AMI), conflicting findings have surfaced through large-scale observational studies and meta-analyses. We conducted this systematic review and meta-analysis of published observational studies to quantify the long-term therapeutic impact of beta-blocker across heterogeneous AMI populations.
Methods: We conducted comprehensive searches of the PubMed, Embase, Cochrane, and Web of Science databases for articles published from 2000 to 2025 that examine the link between beta-blocker therapy and clinical outcomes (last search update: March 1, 2025).
Clin Obes
September 2025
Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland.
Body mass index (BMI) on its own is a poor diagnostic and staging tool for obesity because it does not measure health status. The newly published Lancet Clinical Obesity Criteria (LCOC) for defining clinical obesity distinguish preclinical and clinical obesity based on organ or tissue dysfunction. The King's Obesity Staging System (KOSS) goes further and incorporates biomedical, psychosocial, and economic factors while offering a practical, holistic, and health domain-specific assessment of obesity's impact.
View Article and Find Full Text PDFNutr Metab Cardiovasc Dis
August 2025
Department of Cardiology, Kailuan Hospital, Tangshan, China. Electronic address:
Background And Aims: Diabetes mellitus (DM) commonly coexists with non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD), and when combined with these two conditions, the risk of all-cause mortality and developing cardiovascular diseases (CVD) increases. The present community-based cohort study aimed to elucidate the combined effect of NAFLD and CKD on CVD and mortality risks in new-onset DM patients.
Methods And Results: After the exclusion of participants failing to meet the inclusion criteria, 11,328 eligible participants (mean age: 58.
Diabet Med
September 2025
Edinburgh Centre for Endocrinology & Diabetes, NHS Lothian, Edinburgh, UK.
Aims: This study aimed to assess the impact of the Omnipod 5 automated insulin delivery (AID) system on continuous glucose monitoring (CGM) metrics, HbA1c, and weight in a real-world setting. Additionally, independent predictors of glycaemic response were assessed.
Methods: Observational analysis of adults with type 1 diabetes using Omnipod 5 (n = 353).