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http://dx.doi.org/10.1093/cid/ciad013 | DOI Listing |
J Math Biol
September 2025
Department of Mathematics, University of Illinois Urbana-Champaign, Urbana, USA.
A fundamental question in the field of molecular computation is what computational tasks a biochemical system can carry out. In this work, we focus on the problem of finding the maximum likelihood estimate (MLE) for log-affine models. We revisit a construction due to Gopalkrishnan of a mass-action system with the MLE as its unique positive steady state, which is based on choosing a basis for the kernel of the design matrix of the model.
View Article and Find Full Text PDFFront Psychol
August 2025
Faculty of Information Technology, Monash University, Melbourne, VIC, Australia.
Psychology's crises (e.g., replicability, generalisability) are currently believed to derive from Questionable Research Practices (QRPs), thus scientific misconduct.
View Article and Find Full Text PDFMedEdPublish (2016)
May 2025
Newcastle University Faculty of Medical Sciences, Newcastle upon Tyne, England, UK.
Background: Whilst debriefing literature offers valuable tools for healthcare education, there remains a gap in resources specifically designed for debriefing communication skills. Effective communication is fundamental to patient care, particularly during sensitive interactions. This article provides a specialised toolkit for educators to enhance communication skills debriefing, developed through synthesis of existing literature and the authors' extensive experience teaching communication skills through simulation.
View Article and Find Full Text PDFCuad Bioet
September 2025
Universidad de A Coruña. Facultad de Derecho, Campus de Elviña, s/n, 15071, A Coruña. 981 167000 ext. 1640
The implications of the use of artificial intelligence (AI) in many areas of human existence compels us to reflect on its ethical relevance. This paper addresses the signification of its use in healthcare for patient informed consent. To this end, it first proposes an understanding of AI, as well as the basis for informed consent.
View Article and Find Full Text PDFJ Alzheimers Dis
September 2025
IRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.
The "biological view" of Alzheimer's disease (AD) focuses on the role of plaques and tangles and excludes syndromes from the disease definition. However, cognitive syndromes are fundamental aspects of AD and are the ultimate target of treatments. Accordingly, the study of cognitive syndromes should remain a major goal of AD research.
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