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Dramatic events during the COVID-19 pandemic have acutely impacted the psychosocial environment worldwide, with negative implications for mental health, particularly for more vulnerable children and adolescents with severe psychiatric illnesses. Some data suggest that the pandemic waves may have produced different psychopathological consequences, further worsening in the second phase of the pandemic, compared to those in the first lockdown, soon after March 2020. To test the hypothesis of a further worsening of psychiatric consequences of COVID-19 in the second lockdown compared to the first lockdown, we focused our analysis on a consecutive sample of youth referred to a psychiatric emergency unit for acute mental disorders in the time period between March 2019-March 2021. The sample, consisting of 241 subjects (123 males and 118 females, ranging in age from 11 to 17 years), was divided into three groups: Pre-Lockdown Group (PLG, 115 patients); First Lockdown Group (FLG, 65 patients); and Second Lockdown Group (SLG, 61 patients). Patients in the SLG presented more frequently with non-suicidal self-injuries (NSSIs), suicidal ideation, and suicidal behavior, while no significant differences in self-harm were found between PLG and FLG. Eating disorders were more frequent in both the FLG and SLG, compared to the PLG, while sleep problems were higher only in the SLG. Furthermore, patients in the SLG presented with more frequent psychological maltreatments and neglect, as well as with psychiatric disorders in the parents. Adverse traumatic experiences and internalizing disorders were significantly associated with an increased risk of suicidality. Intellectual disability was less represented from the PLG to SLG, and similarly, the rate of ADHD was lower in the SLG. No differences were found for the other psychiatric diagnoses. This information may be helpful for a better understanding and management of adolescents with severe emotional and behavioral disorders after the exposure to long-lasting collective traumas.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776965 | PMC |
http://dx.doi.org/10.3390/children9121921 | DOI Listing |
Pharmacoepidemiol Drug Saf
September 2025
Sanofi, Cambridge, Massachusetts, USA.
Purpose: Given the increased likelihood for individuals with severe asthma to experience comorbidities, disease complications, emergency room visits, and hospitalizations, the ability to stratify asthma populations on severity is often important. Although pharmacoepidemiologic studies using administrative healthcare databases sometimes categorize asthma severity, there is no consensus on an approach.
Methods: Individuals with asthma (≥ 2 ICD-10-CM diagnosis codes J45) aged ≥ 6 years were identified in Optum's de-identified Clinformatics Data Mart Database between January 2017 and November 2023.
Objective: Estimating the probability of pedestrian injuries at different impact speeds is important for research and regulatory efforts related to infrastructure and vehicle design. However, a risk curve is only valuable if it is based on crash data that accurately represent the current vehicle fleet. This study, therefore, aimed to provide an updated estimate of pedestrian injury risk at different severity levels using recent crash data from U.
View Article and Find Full Text PDFJ Safety Res
September 2025
Department of Civil Engineering, University of Louisiana, Lafayette, LA 70503, USA.
Introduction: Motorized rickshaws are a common mode of urban transportation in many low and middle-income countries, particularly in South Asia (e.g., Pakistan and India).
View Article and Find Full Text PDFJ Safety Res
September 2025
Department of Civil & Environmental Engineering, The University of Tennessee, Knoxville, United States. Electronic address:
Introduction: Despite being prohibited from walking on freeways per federal laws, 14% to 17% of all pedestrian crashes in the United States happen on the interstates. Examining these crashes within the context of the safe systems approach is essential, with an emphasis on mitigating safety risks for all road users. This study investigates the correlates of pedestrian crash injury severity on interstates in North Carolina, focusing on pedestrian actions, roadway conditions, and the type of vehicles involved in the crashes.
View Article and Find Full Text PDFJ Safety Res
September 2025
Faculty of Economics, UNED, Madrid, Spain. Electronic address:
Introduction: In this paper, we examine the relationship between sex and injury severity in car accidents in Spain from 2014 to 2021 using discrete choice models.
Method: We differentiate between no injuries, minor injuries, severe injuries, and fatalities, finding significant gender differences. These results hold even after controlling for vehicle dimensions.