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Purpose: We compared the radiation dose and image quality between the 2nd generation and the 3rd generation dual-source single-energy (DSSE) and dual-source dual-energy (DSDE) CT of the abdomen.
Materials And Methods: We included patients undergoing follow-up abdominal CT after partial or radical nephrectomy in the first 10 months of 2019 (2nd generation DS CT) and the first 10 months of 2020 (3rd generation DS CT). We divided the 320 patients into 4 groups (A, 2nd generation DSSE CT; B, 2nd generation DSDE CT; C, 3rd generation DSSE CT; and D, 3rd generation DSDE CT) ( = 80 each) matched by sex and body mass index. Radiation dose and image quality (objective and subjective qualities) were compared between the groups.
Results: The mean size-specific dose estimation of 3rd generation DSDE CT group was significantly lower than that of the 2nd generation DSSE CT (42.5%, = 0.013) and 2nd generation DSDE CT (46.9%, = 0.015) groups. Interobserver agreement was excellent for the overall image quality (intraclass correlation coefficient [ICC]: 0.8867) and image artifacts (ICC: 0.9423).
Conclusion: Our results showed a considerable reduction in the radiation dose while maintaining high image quality with 3rd generation DSDE CT as compared to the 2nd generation DSDE CT and 2nd generation DSSE CT.
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http://dx.doi.org/10.3348/jksr.2021.0104 | DOI Listing |
Nat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Cell Biol Lipids
September 2025
Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada; Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, V8W 2Y2, Canada; University of Victoria Genome BC Proteomics Centre, Vi
The class I phosphoinositide 3-kinase pathway (PI3K) is a master regulator of cellular growth, and plays essential roles in controlling immune cell function, metabolism, chemotaxis and proliferation. Activation of class I PI3Ks generates the signalling lipid PIP that activates multiple pro-growth signalling pathways. Class I PI3Ks can be activated by multiple plasma membrane stimuli, including G-protein coupled receptors, Ras superfamily GTPases, and receptor tyrosine kinases.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
September 2025
Biomechanics Laboratory, School of Physical Education & Sport Science at Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Purpose: Total knee arthroplasty (TKA) is associated with acute postoperative effects that increase the risk of falls. These effects differ between the medial parapatellar (PP) and mid-vastus (MV) surgical techniques but have not been evaluated in terms of postural sway complexity. Loss of this complexity leads to increased randomness in the center of pressure and higher fall risk.
View Article and Find Full Text PDFInteract J Med Res
September 2025
Department of Medicine, MacKay Medical College, New Taipei, Taiwan.
Background: Dengue fever remains the most significant vector-borne disease in Southeast Asia, imposing a substantial burden on public health systems. Global warming and increased international mobility may exacerbate the disease's prevalence. Furthermore, the unprecedented COVID-19 pandemic may have influenced the epidemiological patterns of dengue.
View Article and Find Full Text PDFClin Exp Dent Res
October 2025
Medical Centre for Orthopaedics and Sports Dentistry, Leipzig, Germany.
Objectives: Dental trauma is a frequent injury in contact sports such as handball an basketball. This study aimed to evaluate preventive measures in dental traumatology and assess the knowledge of medical teams in elite German handball and basketball.
Material And Methods: From March to June 2024, supervisors of 1st and 2nd German Bundesliga handball (HB) and basketball (BB) teams were invited via email to complete an online questionnaire (Socey Survey).