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We investigated the efficacy, safety, and versatility of the AngioVac (AngioDynamics, Latham, NY) system for the treatment of intravascular and intracardiac masses of different origins. We prospectively enrolled all consecutive patients treated with the AngioVac system between July-2016 and November-2021 at our institution. Three configurations of the device were adopted in 44 patients: a venous-venous circuit in 21 cases (47.7%), a venous-arterial ECMO-like configuration in 20 (45.5%), and a venous-arterial-arterial circuit with 2 centrifugal pumps for left-sided cardiac masses in 3 (6.8%). Successful removal of the mass was achieved in 41 patients (93.2%), while in the other cases conversion to full sternotomy was necessary. Intraoperative complications occurred in 3 cases (6.8%), including 1 death, 1 pulmonary embolization, and 1 cardiac perforation. The AngioVac system is a valid, safe, and versatile option for the treatment of intravascular masses also in patients with prohibitive surgical risk.
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http://dx.doi.org/10.1016/j.cpcardiol.2022.101543 | DOI Listing |
JACC Case Rep
September 2025
HonorHealth Thompson Peak Medical Center, Scottsdale, Arizona, USA.
Background: Surgical management is recommended for infective endocarditis (IE) when there is right heart failure due to severe tricuspid regurgitation, recurrent septic pulmonary emboli, persistent bacteremia, and large tricuspid valve vegetations (≥20 mm). However, sternotomy comes with strict eligibility limitations, including poor functional status, respiratory failure, and recent intravenous drug use.
Case Summary: A 55-year-old woman with a history of intravenous drug use was diagnosed with persistent bacteremia in the setting of tricuspid valve endocarditis.
JACC Case Rep
August 2025
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Background: Transcatheter left atrial appendage occlusion (LAAO) is a low-risk procedure with a <1.0% risk of malposition.
Case Summary: An 80-year-old man with atrial fibrillation intolerant to apixaban underwent implantation of a 24 mm Watchman FLX device (Boston Scientific), which immediately shifted, exposing uncovered metal in the left atrium.
JACC Case Rep
July 2025
Department of Cardiology, NCH Rooney Heart Institute, Naples, Florida, USA.
In patients with refractory mitral valve endocarditis who are not surgical candidates, percutaneous debulking is a potential treatment option. We describe the first report of percutaneous mechanical aspiration of prosthetic mechanical mitral valve endocarditis using the AngioVac system and cerebral protection devices.
View Article and Find Full Text PDFKardiol Pol
May 2025
Department of Cardiology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Antoni Jurasz University Hospital No 1, Bydgoszcz, Poland.
Case Rep Cardiol
April 2025
Department of Medicine, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
The AngioVac mechanical aspiration system has emerged in the literature as a viable treatment option for patients with intracardiac masses and thrombi and who are deemed high risk for cardiac surgery. Notably, it has been shown to be an effective treatment modality for the debulking of thrombi in the setting of malignancy. We present a case of repeat AngioVac debulking of a large right atrial thrombus with extension from the hepatic vein in the setting of advanced malignancy complicated by endocarditis.
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