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http://dx.doi.org/10.1016/j.jacc.2022.10.012 | DOI Listing |
Rev Cardiovasc Med
August 2025
Cardiovascular Department, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 100091 Beijing, China.
Background: While the invasive index of microcirculation resistance (IMR) remains the gold standard for diagnosing coronary microvascular dysfunction (CMD), its clinical adoption is limited by procedural complexity and cost. Angiography-based IMR (Angio-IMR), a computational angiography-based method, offers a promising alternative. This study evaluates the diagnostic efficacy of Angio-IMR for CMD detection in angina pectoris (AP).
View Article and Find Full Text PDFClin Res Cardiol
September 2025
Department of (Interventional) Cardiology, Thoraxcenter, Erasmus University Medical Center, Room Rg-628, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
Background: Fractional flow reserve (FFR) for non-culprit lesions (NCLs) in patients with ST-elevation myocardial infarction (STEMI) can be influenced by temporary changes in microvascular resistance. Angiography-derived vessel fractional flow reserve (vFFR) has been tested as a less-invasive alternative.
Aims: The FAST STEMI II study aimed to assess the diagnostic performance of acute-setting vFFR vs.
Coron Artery Dis
August 2025
Division of Cardiology, Department of Medicine, Taipei Veteran General Hospital.
Background: Vessel fractional flow reserve (vFFR) is an angiography-based assessment for coronary physiology. vFFR can be measured at baseline and after percutaneous coronary intervention (PCI). Residual vFFR, a feature designed to predict post-PCI vFFR following stent implantation, can be utilized for PCI planning.
View Article and Find Full Text PDFAtherosclerosis
August 2025
Polito(BIO) Med Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Background: The relationship between traditional risk factors, translesional hemodynamics, and plaque vulnerability remains incompletely understood. Endothelial shear stress (ESS) has recently emerged among the key players determining lesions instability and cardiovascular risk.
Aims: We aimed to evaluate the prognostic value of ESS-based quantities and their interplay with anatomical and clinical factors in predicting adverse cardiovascular events in older patients with multivessel coronary artery disease (MVD).
Int J Cardiol
August 2025
First Department of Cardiology, Medical University of Warsaw, Warsaw, Poland. Electronic address:
Background: Post-procedural three-dimensional (3D) quantitative coronary angiography (QCA)-based vessel fractional flow reserve (vFFR) has shown a strong correlation with invasive FFR measurements. However, the relationship between post-percutaneous coronary intervention (PCI) vFFR, vFFR-derived pressure pullback gradient (PPG), clinical outcomes, and post-PCI quality of life (QoL) concerning sex differences remains unexplored.
Methods: This single-centre retrospective study included patients undergoing PCI for stable or unstable angina, or non-ST-elevation myocardial infarction (NSTEMI) with two angiographic views suitable for post-PCI vFFR calculation and complete QoL assessment.