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Background: In prepectoral direct-to-implant breast reconstruction using the acellular dermal matrix (ADM)-assisted technique, breast volume asymmetry can occur. We hypothesized that ADM size influences implant size selection in prepectoral breast reconstruction with implant coverage using an ADM. We investigated factors influencing implant size selection and provide guidelines for surgeons.
Methods: A retrospective chart review was performed to identify all patients who underwent prepectoral direct-to-implant breast reconstruction between January 2017 and October 2020. We assessed patient characteristics, preoperative expected implant volume, ADM size, volume of implant used in surgery, and symmetry scale of aesthetic item scale (AIS) 6 months after surgery. We compared the symmetry score of AIS between a group in which the preoperative expected silicone implant size (ES) was used and a group in which a silicone implant of a smaller size than planned (SS) was used.
Results: Patient characteristics, including age, body mass index (BMI), and excised breast volume, were similar between the groups (P > .05). ADM size had a significant effect on implant size selection (odds ratio = 1.760, P < .01). The symmetry score of AIS was higher in the SS group.
Conclusions: ADM size must be considered when selecting implant size in prepectoral direct-to-implant breast reconstruction using the ADM-assisted technique.
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http://dx.doi.org/10.1097/MD.0000000000031344 | DOI Listing |
ACS Chem Neurosci
September 2025
Chemical and Biomolecular Engineering Dept, University of California, Los Angeles, Los Angeles, California 90095, United States.
Simulations in three dimensions and time provide guidance on implantable, electroenzymatic glutamate sensor design; relative placement in planar sensor arrays; feasibility of sensing synaptic release events; and interpretation of sensor data. Electroenzymatic sensors based on the immobilization of oxidases on microelectrodes have proven valuable for the monitoring of neurotransmitter signaling in deep brain structures; however, the complex extracellular milieu featuring slow diffusive mass transport makes rational sensor design and data interpretation challenging. Simulations show that miniaturization of the disk-shaped device size below a radius of ∼25 μm improves sensitivity, spatial resolution, and the accuracy of glutamate concentration measurements based on calibration factors determined .
View Article and Find Full Text PDFJ Prosthodont
September 2025
Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Purpose: This study aimed to evaluate the inherent and after cyclic loading fracture strength of implant-supported cantilevered fixed prostheses fabricated from recently introduced additively manufactured (AM) and subtractively manufactured (SM) materials, considering variations in prosthesis height.
Materials And Methods: Three cylinder-shaped master files (20 mm long and 11 mm wide) with varying heights (7, 11, and 15 mm) and a titanium-base (Ti-base) abutment space were designed. These designs were used to fabricate a total of 144 specimens with two AM resins indicated for definitive use (Crowntec; AM-CT and Flexcera Smile Ultra+; AM-FS), one high-impact polymer composite (breCAM.
J Prosthodont
September 2025
Department of Community Medicine and Health Care, University of Connecticut Health Center, Farmington, Connecticut, USA.
Purpose: The purpose of this study was to evaluate the survival outcomes of dental implants placed in the pterygoid region and assess the potential influence of multiple clinical variables on their survival.
Materials And Methods: A retrospective chart review was conducted on pterygoid implants placed over a 9-year period at the University of Connecticut Department of Prosthodontics. All pterygoid implants were placed by a single board-certified prosthodontist following a standardized surgical protocol.
Regen Med
September 2025
Symbiosis Centre for Stem Cell Research (SCSCR), Symbiosis School of Biological Sciences (SSBS), Symbiosis International, Deemed University, Lavale, Pune, India.
Aims: This study aimed to enhance the osteoinductive potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) by integrating them into a nano-hydroxyapatite (nHAp)-enriched hydrogel scaffold for bone regeneration applications.
Materials & Methods: EVs were isolated from naïve and osteogenically primed MSCs and characterized for morphology, cargo content, and cytocompatibility. Their uptake and osteoinductive activity were assessed using MC3T3 cells within a 3D interpenetrating network (IPN) hydrogel.
Int J Oral Implantol (Berl)
September 2025
Purpose: To compare the accuracy of static guided surgery using a pilot drill guide and dynamic guided surgery for dental implant placement.
Materials And Methods: Partially edentulous adult patients requiring implant placement were randomly assigned to either the static guided surgery group using a pilot drill guide or the dynamic guided surgery group. Digital implant planning was conducted using intraoral scans and CBCT with planning software to determine the optimal prosthetic position.