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The anatomy and technique of free muscle flaps - in particular gracilis flap and latissimus dorsi flap - in lower extremity reconstruction have been well described. There is a paucity of data on potential risk factors in larger patient series that affect the outcome. The objective of this study was to address this lack of knowledge by reporting outcomes and complications of free muscle flaps as a primary option in lower extremity reconstruction. From 2009 to 2020, a total of 253 consecutive patients with soft tissue defects of the lower limb from trauma, infection or malignancies underwent lower extremity reconstructive surgery with 266 free muscle flaps. Complications requiring revision surgery were noted in 36.1% of cases. Total flap loss occurred in 10.5% of cases. Patients requiring revision surgery were older, more likely to be female, more likely to be active smokers, and more likely to have a higher ASA score. Lower extremity reconstruction with free muscle flaps has a relevant complication rate that both patient and reconstructive surgeon need to be aware of. Prospective studies should try to further assess the factors affecting the outcome.
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http://dx.doi.org/10.1080/2000656X.2022.2142599 | DOI Listing |
J Strength Cond Res
September 2025
Institute for Data Analysis and Process Design, ZHAW, Zurich, Switzerland; and.
Achermann, BB, Drewek, A, and Lorenzetti, SR. Acute effect of the bounce squat on ground reaction force at the turning point and barbell kinematics. J Strength Cond Res XX(X): 000-000, 2025-The free-weight back squat is a key exercise for developing lower-body strength, with variations that influence muscle activation and performance.
View Article and Find Full Text PDFImmunotherapy
September 2025
Department of Dermatology and Allergology, University Hospital, LMU Munich, Munich, Germany.
Currently, the first-line treatment of non-metastatic Merkel cell carcinoma (MCC) is complete resection. In case of unresectable or metastatic MCC, immune checkpoint inhibitor (ICI) therapy with avelumab (or in the US also pembrolizumab or retifanlimab) is indicated. We report on a patient with a primary, non-metastatic MCC on the left eyelid and amyotrophic lateral sclerosis (ALS).
View Article and Find Full Text PDFLaryngoscope
September 2025
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology/Head and Neck Surgery, University of North Carolina, North Carolina, USA.
The choice of a donor nerve to innervate a free gracilis muscle transfer (FMGT) is more complicated in patients with a history of previous facial paralysis surgeries. This case report describes the use of the deep temporal nerve to successfully power a FMGT in a nerve-depleted patient.
View Article and Find Full Text PDFAnn Afr Med
September 2025
Department of Pediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Background And Aims: Hypothyroid patients often complain of shortness of breath, fatigue, and exercise intolerance. Both inspiratory and expiratory muscles' weakness is present, and the impairment of pulmonary function may be initiated at the subclinical stage of hypothyroidism. Hence, this study aimed to assess the pulmonary function tests (PFTs) in hypothyroid patients.
View Article and Find Full Text PDFPain Manag
September 2025
Serviço de Reabilitação de Adultos 3, Centro de Medicina de Reabilitação de Alcoitão, Alcabideche, Portugal.
Pudendal neuropathy is a cause of pelvic pain, specifically pudendal neuralgia. The pudendal nerve is related to sensory, motor, and autonomic functions. We present the case of a 41-year-old man who suffered from chronic pelvic pain.
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