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Objectives: Ischemic remodeling of the left ventricle in patients with coronary artery disease (CAD) results in geometric changes of the mitral valve (MV) apparatus, leading to reduced MV leaflet coaptation. Although the calculation of the coaptation area has value in assessing the effects of left ventricular remodeling on the MV, it is difficult and time-consuming to measure. In this study the authors hypothesized that the tenting volume (TV) would have a greater association with coaptation area than tenting height (TH) or tenting area (TA).
Design: A retrospective review.
Setting: A single tertiary-care academic hospital.
Participants: There were 145 adult patients who underwent coronary artery bypass graft surgery between April 2018 and July 2020.
Measurements And Main Results: Intraoperative 2- and 3-dimensional transesophageal echocardiographic studies were obtained in the precardiopulmonary bypass period. Offline analysis was used to obtain TH, TA, TV and coaptation area for each patient. Correlation between the coaptation area and the TH, TA, and TV was conducted using Pearson's correlation. The median age of the population was 68.0 years (61.0-73.3), the body mass index was 29.0 kg/m (25.7-33.5), and 17.8% were females. Increases in TV were the most reliable predictor of decreases in coaptation area (R = 0.75) followed by TA (R = 0.48) and TH (R = 0.47).
Conclusion: As a representative of the complete topography of the MV, the authors' study demonstrated that in patients with CAD, TV has a greater negative correlation with coaptation area as compared to TH or TA.
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http://dx.doi.org/10.1053/j.jvca.2022.10.003 | DOI Listing |
Comput Biol Med
September 2025
Department of Biomedical Engineering & Physics, Amsterdam University Medical Center, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands; Informatics Institute, University of Amsterdam, Science Park 900, Amsterdam, 1098 XH, The Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam University Med
Accurate segmentation of the mitral valve in transthoracic echocardiography (TTE) enables the extraction of various anatomical parameters that are important for guiding clinical management. However, manual mitral valve segmentation is time-consuming and prone to interobserver variability. To support robust automatic analysis of mitral valve anatomy, we propose a novel AI-based method for mitral valve segmentation and anatomical measurement extraction.
View Article and Find Full Text PDFHand (N Y)
August 2025
The Curtis National Hand Center, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Background: Two of the most prevalent techniques for tendon transfer are Pulvertaft weave (PTW) and side-to-side (STS) constructs. Our purpose was to compare pooled results from reported biomechanical properties of these approaches by a meta-analysis. Our null hypothesis was there are no significant differences in load to failure (LTF), initial construct stiffness, or cross-sectional area (CSA) between these techniques.
View Article and Find Full Text PDFJ Pediatr Soc North Am
August 2025
Texas Scottish Rite Hospital for Children, Dallas, TX, USA.
Unlabelled: The purpose of this chapter is to provide a basic instructional reference for upper extremity splint application in the context of pediatric orthopaedic trauma. In addition to reviewing the steps necessary for successful splint application, this chapter will also discuss common pitfalls to avoid in order to optimize outcomes and prevent complications during and after splint immobilization for upper extremity injuries. Embedded throughout the chapter are figures and videos that highlight how to apply various splints to the upper extremity based on the injury location and the immobilization required for different clinical situations.
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
August 2025
Division of Thoracic and Cardiovascular Surgery, CHU Reims, Rue du General Koenig, Reims, 51100, France.
Objectives: Repairing severe mitral regurgitation (MR) in patients with degenerative bileaflet prolapse and reduced left ventricular ejection fraction (LVrEF) is challenging. The Free Margin Running Suture (FMRS) technique offers a non-resectional approach, but mid-term data are limited.
Methods: We analysed 28 patients with bileaflet degenerative MR and LVrEF (≤40%) undergoing FMRS.
J Clin Med
July 2025
Cardiology Department, Université of Rennes, CHU Rennes, Inserm, LTSI-UMR 1099, F-35000 Rennes, France.
Mitral regurgitation (MR) is a common valvular heart disease associated with significant morbidity and mortality. For patients at high or prohibitive surgical risk, mitral transcatheter edge-to-edge repair (M-TEER) offers a less invasive alternative to surgery. This review outlines key aspects of patient selection and procedural planning for M-TEER, with a focus on clinical and echocardiographic criteria essential for success.
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