98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877887 | PMC |
http://dx.doi.org/10.1002/pds.5560 | DOI Listing |
J Nephrol
September 2025
Institute of Nephrology, Madras Medical College, Chennai, India.
Background: IgA nephropathy is a disease with a highly variable natural history, for which there is an increasing understanding of the role of complement activation in its pathogenesis and progression. We aimed to assess the clinical and prognostic implications of C4d staining in the kidney biopsy of IgA nephropathy patients.
Methods: This was a retrospective observational study wherein the medical records of IgA nephropathy patients were reviewed and baseline characteristics, kidney biopsy findings, treatment response and follow-up data were noted.
J Behav Med
September 2025
Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 7039, Cincinnati, OH, 45229, USA.
Randomized pretest, posttest, follow-up (RPPF) designs are widely used in longitudinal behavioral intervention research to evaluate the efficacy of treatments over time. These designs typically involve random assignment of participants to treatment and control conditions, with assessments conducted at baseline, immediately post-intervention, and during the follow-up period. Researchers primarily focus on determining whether the intervention is more effective than the control condition at post-treatment and whether these effects are sustained or change over time.
View Article and Find Full Text PDFEur J Clin Pharmacol
September 2025
Department of Clinical Pharmacy and Pharmacology, University of Groningen, and University Medical Center Groningen, Groningen, The Netherlands.
Purpose: Non-adherence to inhaled medication poses a significant clinical and economic burden on patients with respiratory diseases. This narrative review provides an overview of key aspects of hair analysis, in general and specific for inhaled medications, and explores the potential of hair analysis as a novel tool to monitor adherence to inhaled medications.
Methods: PubMed searches were conducted to explore four aspects: (1) mechanisms of (inhaled) drug's systemic absorption and deposition in hair; (2) quantification of drugs in hair; (3) factors impacting (inhaled) drug hair concentrations; and (4) clinical studies assessing inhaled medication adherence through hair analysis.
JMIR Form Res
September 2025
Department of Critical Care Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Provincial Geriatrics Institute, No. 106, Zhongshaner Rd, Guangzhou, 510080, China, 86 15920151904.
Background: Point-of-care ultrasonography has become a valuable tool for assessing diaphragmatic function in critically ill patients receiving invasive mechanical ventilation. However, conventional diaphragm ultrasound assessment remains highly operator-dependent and subjective. Previous research introduced automatic measurement of diaphragmatic excursion and velocity using 2D speckle-tracking technology.
View Article and Find Full Text PDFJ Interpers Violence
September 2025
University of Memphis, TN, USA.
Complex trauma (CT), or chronic interpersonal trauma that begins early in life, has been associated with a multitude of negative outcomes, including posttraumatic stress symptoms (PTSS) and emotion dysregulation. Some CT survivors also exhibit adaptive functioning, such as resilience. Social and contextual factors may have an impact on the expression of adverse and adaptive outcomes for CT survivors, yet have been neglected.
View Article and Find Full Text PDF